TY - JOUR
T1 - Vitamin D and Physical Performance in Older Men and Women Visiting the Emergency Department Because of a Fall: Data from the Improving Medication Prescribing to reduce Risk Of FALLs (IMPROveFALL) Study
AU - Boye, N.D.A.
AU - Oudshoorn, C.
AU - van der Velde, N.
AU - van Lieshout, E.M.M.
AU - de Vries, O.J.
AU - Lips, P.T.A.M.
AU - van Beeck, E.F.
AU - Patka, P.
AU - van der Cammen, T.J.M.
PY - 2013
Y1 - 2013
N2 - Objectives To investigate whether serum 25-hydroxy vitamin D (25(OH)D) is associated with physical performance in men and women. Design Cross-sectional. Setting Emergency departments (EDs) of five hospitals. Participants Older adults who visited an ED because of a fall (N = 616). Measurements Physical performance was assessed using the Timed Up and Go Test, the Five Time Sit to Stand Test, handgrip strength, and the tandem stand test. Multivariate linear regression was used to assess the association between physical performance and log-transformed 25(OH)D concentration adjusted for potential confounders. Results In men, higher serum 25(OH)D concentration was significantly associated with better handgrip strength (regression coefficient (B) = 3.86, 95% confidence interval (CI) = 2.04-5.69), faster TUG time (B = -2.82, 95% CI = -4.91 to -0.73), and faster FTSS time (B = -3.39, 95% CI = -5.67 to -1.11). In women, higher serum 25(OH)D concentration was significantly associated with faster TUG time (B = -2.68, 95% CI = -4.87 to -0.49). Conclusion A positive association was found between serum 25(OH)D level and physical performance in men and women. Intervention studies are needed of vitamin D-deficient older men and women to further investigate the effect of vitamin D supplementation in this group. © 2013, The American Geriatrics Society.
AB - Objectives To investigate whether serum 25-hydroxy vitamin D (25(OH)D) is associated with physical performance in men and women. Design Cross-sectional. Setting Emergency departments (EDs) of five hospitals. Participants Older adults who visited an ED because of a fall (N = 616). Measurements Physical performance was assessed using the Timed Up and Go Test, the Five Time Sit to Stand Test, handgrip strength, and the tandem stand test. Multivariate linear regression was used to assess the association between physical performance and log-transformed 25(OH)D concentration adjusted for potential confounders. Results In men, higher serum 25(OH)D concentration was significantly associated with better handgrip strength (regression coefficient (B) = 3.86, 95% confidence interval (CI) = 2.04-5.69), faster TUG time (B = -2.82, 95% CI = -4.91 to -0.73), and faster FTSS time (B = -3.39, 95% CI = -5.67 to -1.11). In women, higher serum 25(OH)D concentration was significantly associated with faster TUG time (B = -2.68, 95% CI = -4.87 to -0.49). Conclusion A positive association was found between serum 25(OH)D level and physical performance in men and women. Intervention studies are needed of vitamin D-deficient older men and women to further investigate the effect of vitamin D supplementation in this group. © 2013, The American Geriatrics Society.
U2 - https://doi.org/10.1111/jgs.12499
DO - https://doi.org/10.1111/jgs.12499
M3 - Article
C2 - 24116657
SN - 0002-8614
VL - 61
SP - 1948
EP - 1952
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
IS - 11
ER -