Vitamin K-dependent carboxylases from non-hepatic tissues

C. Vermeer; H. Hendrix; M. Daemen

doi:https://doi.org/10.1016/0014-5793(82)80832-6

Vitamin K-dependent carboxylases from non-hepatic tissues

C. Vermeer, H. Hendrix, M. Daemen

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Research output: Contribution to journal › Article › Academic › peer-review

39 Citations (Scopus)

Abstract

The presence of vitamin K-dependent carboxylase was investigated in the microsomal fraction of 20 different types of bovine tissue. Except for muscle, veins, lymphocytes and bone membrane, carboxylase was found in all these preparations, albeit in varying amounts. No differences could be detected between these carboxylating systems with respect to their affinity for vitamin K and warfarin. Most of the endogenous substrates had some affinity towards antiprothrombin or antifactor X

Original language	English
Pages (from-to)	317-320
Journal	FEBS letters
Volume	148
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(82)80832-6
Publication status	Published - 1982

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https://doi.org/10.1016/0014-5793(82)80832-6

Cite this

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title = "Vitamin K-dependent carboxylases from non-hepatic tissues",

abstract = "The presence of vitamin K-dependent carboxylase was investigated in the microsomal fraction of 20 different types of bovine tissue. Except for muscle, veins, lymphocytes and bone membrane, carboxylase was found in all these preparations, albeit in varying amounts. No differences could be detected between these carboxylating systems with respect to their affinity for vitamin K and warfarin. Most of the endogenous substrates had some affinity towards antiprothrombin or antifactor X",

author = "C. Vermeer and H. Hendrix and M. Daemen",

year = "1982",

doi = "https://doi.org/10.1016/0014-5793(82)80832-6",

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T1 - Vitamin K-dependent carboxylases from non-hepatic tissues

AU - Vermeer, C.

AU - Hendrix, H.

AU - Daemen, M.

PY - 1982

Y1 - 1982

N2 - The presence of vitamin K-dependent carboxylase was investigated in the microsomal fraction of 20 different types of bovine tissue. Except for muscle, veins, lymphocytes and bone membrane, carboxylase was found in all these preparations, albeit in varying amounts. No differences could be detected between these carboxylating systems with respect to their affinity for vitamin K and warfarin. Most of the endogenous substrates had some affinity towards antiprothrombin or antifactor X

AB - The presence of vitamin K-dependent carboxylase was investigated in the microsomal fraction of 20 different types of bovine tissue. Except for muscle, veins, lymphocytes and bone membrane, carboxylase was found in all these preparations, albeit in varying amounts. No differences could be detected between these carboxylating systems with respect to their affinity for vitamin K and warfarin. Most of the endogenous substrates had some affinity towards antiprothrombin or antifactor X

U2 - https://doi.org/10.1016/0014-5793(82)80832-6

DO - https://doi.org/10.1016/0014-5793(82)80832-6

M3 - Article

C2 - 7152026

SN - 0014-5793

VL - 148

SP - 317

EP - 320

JO - FEBS letters

JF - FEBS letters

IS - 2

ER -