Vizelet cytokinek koncentrációjának változása felületes hólyagdaganatok immunterápiája során

L. Somogyi; E. C. de Boer; G. J. de Ruiter; T. M. de Reijke; K. H. Kurth; D. H. Schamhart

Vizelet cytokinek koncentrációjának változása felületes hólyagdaganatok immunterápiája során

L. Somogyi, E. C. de Boer, G. J. de Ruiter, T. M. de Reijke, K. H. Kurth, D. H. Schamhart

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Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A growing number of data support the importance of urinary cytokines in the BCG immunotherapy of superficial bladder tumours. To investigate kinetics and stability, urinary levels of IL-8, IL-2 and IL-6 cytokines after BCG treatment, were determined. Significant elevation in the level of IL-8 was established immediately following the first BCG instillation and it reached its highest value 4-6 hours after the treatment. During the first three weeks of the treatment and follow-up period IL-8 peaked significantly earlier than IL-2 or IL-6. Its early appearance associated with high stability makes IL-8 a good candidate for being considered as an effective agent with high predictive value in BCG immunotherapy

Original language	English
Pages (from-to)	67-69
Journal	Orvosi hetilap
Volume	139
Issue number	2
Publication status	Published - 1998

Cite this

@article{6ef52dac9380443bae3dcb9036a119e0,

title = "Vizelet cytokinek koncentr{\'a}ci{\'o}j{\'a}nak v{\'a}ltoz{\'a}sa fel{\"u}letes h{\'o}lyagdaganatok immunter{\'a}pi{\'a}ja sor{\'a}n",

abstract = "A growing number of data support the importance of urinary cytokines in the BCG immunotherapy of superficial bladder tumours. To investigate kinetics and stability, urinary levels of IL-8, IL-2 and IL-6 cytokines after BCG treatment, were determined. Significant elevation in the level of IL-8 was established immediately following the first BCG instillation and it reached its highest value 4-6 hours after the treatment. During the first three weeks of the treatment and follow-up period IL-8 peaked significantly earlier than IL-2 or IL-6. Its early appearance associated with high stability makes IL-8 a good candidate for being considered as an effective agent with high predictive value in BCG immunotherapy",

author = "L. Somogyi and {de Boer}, {E. C.} and {de Ruiter}, {G. J.} and {de Reijke}, {T. M.} and Kurth, {K. H.} and Schamhart, {D. H.}",

year = "1998",

language = "English",

volume = "139",

pages = "67--69",

journal = "Orvosi hetilap",

issn = "0030-6002",

publisher = "Akad{\'e}miai Kiad{\'o}",

number = "2",

}

TY - JOUR

T1 - Vizelet cytokinek koncentrációjának változása felületes hólyagdaganatok immunterápiája során

AU - Somogyi, L.

AU - de Boer, E. C.

AU - de Ruiter, G. J.

AU - de Reijke, T. M.

AU - Kurth, K. H.

AU - Schamhart, D. H.

PY - 1998

Y1 - 1998

N2 - A growing number of data support the importance of urinary cytokines in the BCG immunotherapy of superficial bladder tumours. To investigate kinetics and stability, urinary levels of IL-8, IL-2 and IL-6 cytokines after BCG treatment, were determined. Significant elevation in the level of IL-8 was established immediately following the first BCG instillation and it reached its highest value 4-6 hours after the treatment. During the first three weeks of the treatment and follow-up period IL-8 peaked significantly earlier than IL-2 or IL-6. Its early appearance associated with high stability makes IL-8 a good candidate for being considered as an effective agent with high predictive value in BCG immunotherapy

AB - A growing number of data support the importance of urinary cytokines in the BCG immunotherapy of superficial bladder tumours. To investigate kinetics and stability, urinary levels of IL-8, IL-2 and IL-6 cytokines after BCG treatment, were determined. Significant elevation in the level of IL-8 was established immediately following the first BCG instillation and it reached its highest value 4-6 hours after the treatment. During the first three weeks of the treatment and follow-up period IL-8 peaked significantly earlier than IL-2 or IL-6. Its early appearance associated with high stability makes IL-8 a good candidate for being considered as an effective agent with high predictive value in BCG immunotherapy

M3 - Article

C2 - 9451905

SN - 0030-6002

VL - 139

SP - 67

EP - 69

JO - Orvosi hetilap

JF - Orvosi hetilap

IS - 2

ER -