What is the cause of pulmonary oedema after acute myocardial infarction?: A case study

P G Raijmakers; J J Bax; A B Groeneveld; F C Visser; G J Teule; L G Thijs

What is the cause of pulmonary oedema after acute myocardial infarction? A case study

P G Raijmakers, J J Bax, A B Groeneveld, F C Visser, G J Teule, L G Thijs

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Scopus)

Abstract

A patient is described with an acute myocardial infarction (AMI) and pulmonary oedema, necessitating mechanical ventilation, at a mean pulmonary capillary wedge pressure (PCWP) below 13 mmHg. The 67Ga-transferrin pulmonary leak index (PLI), a measure of microvascular permeability, was normal. A study of the course of the PCWP revealed intermittent elevations up to 22 mmHg, owing to intermittent mitral regurgitation. Pulmonary oedema after an AMI can thus be caused by pressure factors, even at sporadic elevations of PCWP, following intermittent, ischaemia-induced dysfunction of the posterior papillary muscle. Conversely, the measurement of a normal 67Ga-PLI may help to diagnose hydrostatic as opposed to permeability pulmonary oedema, if sporadic elevations of the PCWP are not recognised.

Original language	English
Pages (from-to)	591-2
Number of pages	2
Journal	Intensive care medicine
Volume	22
Issue number	6
Publication status	Published - Jun 1996

Keywords

Capillary Permeability
Gallium Radioisotopes
Humans
Male
Middle Aged
Mitral Valve
Mitral Valve Insufficiency/complications
Myocardial Infarction/complications
Papillary Muscles/physiopathology
Pulmonary Edema/diagnosis
Pulmonary Edema/etiology
Pulmonary Wedge Pressure
Respiration, Artificial
ischaemic heart disease

Cite this

@article{e93958ff4aa14ef69284b492ce6229df,

title = "What is the cause of pulmonary oedema after acute myocardial infarction?: A case study",

abstract = "A patient is described with an acute myocardial infarction (AMI) and pulmonary oedema, necessitating mechanical ventilation, at a mean pulmonary capillary wedge pressure (PCWP) below 13 mmHg. The 67Ga-transferrin pulmonary leak index (PLI), a measure of microvascular permeability, was normal. A study of the course of the PCWP revealed intermittent elevations up to 22 mmHg, owing to intermittent mitral regurgitation. Pulmonary oedema after an AMI can thus be caused by pressure factors, even at sporadic elevations of PCWP, following intermittent, ischaemia-induced dysfunction of the posterior papillary muscle. Conversely, the measurement of a normal 67Ga-PLI may help to diagnose hydrostatic as opposed to permeability pulmonary oedema, if sporadic elevations of the PCWP are not recognised.",

keywords = "Capillary Permeability, Gallium Radioisotopes, Humans, Male, Middle Aged, Mitral Valve, Mitral Valve Insufficiency/complications, Myocardial Infarction/complications, Papillary Muscles/physiopathology, Pulmonary Edema/diagnosis, Pulmonary Edema/etiology, Pulmonary Wedge Pressure, Respiration, Artificial, ischaemic heart disease",

author = "Raijmakers, {P G} and Bax, {J J} and Groeneveld, {A B} and Visser, {F C} and Teule, {G J} and Thijs, {L G}",

year = "1996",

month = jun,

language = "English",

volume = "22",

pages = "591--2",

journal = "Intensive care medicine",

issn = "0342-4642",

publisher = "Springer Verlag",

number = "6",

}

TY - JOUR

T1 - What is the cause of pulmonary oedema after acute myocardial infarction?

T2 - A case study

AU - Raijmakers, P G

AU - Bax, J J

AU - Groeneveld, A B

AU - Visser, F C

AU - Teule, G J

AU - Thijs, L G

PY - 1996/6

Y1 - 1996/6

N2 - A patient is described with an acute myocardial infarction (AMI) and pulmonary oedema, necessitating mechanical ventilation, at a mean pulmonary capillary wedge pressure (PCWP) below 13 mmHg. The 67Ga-transferrin pulmonary leak index (PLI), a measure of microvascular permeability, was normal. A study of the course of the PCWP revealed intermittent elevations up to 22 mmHg, owing to intermittent mitral regurgitation. Pulmonary oedema after an AMI can thus be caused by pressure factors, even at sporadic elevations of PCWP, following intermittent, ischaemia-induced dysfunction of the posterior papillary muscle. Conversely, the measurement of a normal 67Ga-PLI may help to diagnose hydrostatic as opposed to permeability pulmonary oedema, if sporadic elevations of the PCWP are not recognised.

AB - A patient is described with an acute myocardial infarction (AMI) and pulmonary oedema, necessitating mechanical ventilation, at a mean pulmonary capillary wedge pressure (PCWP) below 13 mmHg. The 67Ga-transferrin pulmonary leak index (PLI), a measure of microvascular permeability, was normal. A study of the course of the PCWP revealed intermittent elevations up to 22 mmHg, owing to intermittent mitral regurgitation. Pulmonary oedema after an AMI can thus be caused by pressure factors, even at sporadic elevations of PCWP, following intermittent, ischaemia-induced dysfunction of the posterior papillary muscle. Conversely, the measurement of a normal 67Ga-PLI may help to diagnose hydrostatic as opposed to permeability pulmonary oedema, if sporadic elevations of the PCWP are not recognised.

KW - Capillary Permeability

KW - Gallium Radioisotopes

KW - Humans

KW - Male

KW - Middle Aged

KW - Mitral Valve

KW - Mitral Valve Insufficiency/complications

KW - Myocardial Infarction/complications

KW - Papillary Muscles/physiopathology

KW - Pulmonary Edema/diagnosis

KW - Pulmonary Edema/etiology

KW - Pulmonary Wedge Pressure

KW - Respiration, Artificial

KW - ischaemic heart disease

M3 - Article

C2 - 8814478

SN - 0342-4642

VL - 22

SP - 591

EP - 592

JO - Intensive care medicine

JF - Intensive care medicine

IS - 6

ER -