TY - JOUR
T1 - Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010
AU - Lipsitz, Rebecca
AU - Garges, Susan
AU - Aurigemma, Rosemarie
AU - Baccam, Prasith
AU - Blaney, David D.
AU - Cheng, Allen C.
AU - Currie, Bart J.
AU - Dance, David
AU - Gee, Jay E.
AU - Larsen, Joseph
AU - Limmathurotsakul, Direk
AU - Morrow, Meredith G.
AU - Norton, Robert
AU - O'Mara, Elizabeth
AU - Peacock, Sharon J.
AU - Pesik, Nicki
AU - Rogers, L. Paige
AU - Schweizer, Herbert P.
AU - Steinmetz, Ivo
AU - Tan, Gladys
AU - Tan, Patrick
AU - Wiersinga, W. Joost
AU - Wuthiekanun, Vanaporn
AU - Smith, Theresa L.
PY - 2012
Y1 - 2012
N2 - The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options
AB - The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options
U2 - https://doi.org/10.3201/eid1812.120638
DO - https://doi.org/10.3201/eid1812.120638
M3 - Article
C2 - 23171644
SN - 1080-6040
VL - 18
SP - e2
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 12
ER -