Research output per year
Research output per year
Personal profile
Research interests
I am a senior postdoc (NWO Veni laureate) in fundamental and translational immunology with an extensive experience in cancer and autoimmunity research. My research focuses on developing novel therapeutic nanovaccines, by harnessing dendritic cells to drive anti-cancer immune responses or to dampen in autoimmune diseases.
specialisation
Immunology / Dendritic cells / Cancer / Autoimmunity
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes
Affandi, A. J., Grabowska, J., Olesek, K., Venegas, M. L., Barbaria, A., Rodríguez, E., Mulder, P. P. G., Pijffers, H. J., Ambrosini, M., Kalay, H., O’Toole, T., Zwart, E. S., Kazemier, G., Nazmi, K., Bikker, F. J., Stöckl, J., van den Eertwegh, A. J. M., de Gruijl, T. D., Storm, G., van Kooyk, Y., & 2 others, 3 Nov 2020, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117, 44, p. 27528-27539 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access45 Citations (Scopus) -
CD169 Defines Activated CD14+ Monocytes With Enhanced CD8+ T Cell Activation Capacity
Affandi, A. J., Olesek, K., Grabowska, J., Nijen Twilhaar, M. K., Rodríguez, E., Saris, A., Zwart, E. S., Nossent, E. J., Kalay, H., de Kok, M., Kazemier, G., Stöckl, J., van den Eertwegh, A. J. M., de Gruijl, T. D., Garcia-Vallejo, J. J., Storm, G., van Kooyk, Y. & den Haan, J. M. M., 28 Jul 2021, In: Frontiers in immunology. 12, p. 697840 697840.Research output: Contribution to journal › Article › Academic › peer-review
Open Access23 Citations (Scopus) -
Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis
Affandi, A. J., Carvalheiro, T., Ottria, A., Broen, J. C. A., Bossini-Castillo, L., Tieland, R. G., Bon, L. V., Chouri, E., Rossato, M., Mertens, J. S., Garcia, S., Pandit, A., de Kroon, L. M. G., Christmann, R. B., Martin, J., van Roon, J. A. G., Radstake, T. R. D. J. & Marut, W., 1 Sept 2019, In: Annals of the rheumatic diseases. 78, 9, p. 1249-1259Research output: Contribution to journal › Article › Academic › peer-review
16 Citations (Scopus) -
CXCL4 drives fibrosis by promoting several key cellular and molecular processes
Affandi, A. J., Carvalheiro, T., Ottria, A., de Haan, J. J., Brans, M. A. D., Brandt, M. M., Tieland, R. G., Lopes, A. P., Fernandez, B. M., Bekker, C. P. J., van der Linden, M., Zimmermann, M., Giovannone, B., Wichers, C. G. K., Garcia, S., de Kok, M., Stifano, G., Xu, Y. J., Kowalska, M. A., Waasdorp, M., & 6 others, 4 Jan 2022, In: Cell reports. 38, 1, 22 p., 110189.Research output: Contribution to journal › Article › Academic › peer-review
Open Access23 Citations (Scopus) -
Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis
Van Bon, L., Affandi, A. J., Broen, J. C. A., Christmann, R. B., Marijnissen, R. J., Stawski, L., Farina, G. A., Stifano, G., Mathes, A. L., Cossu, M., York, M., Collins, C., Wenink, M., Huijbens, R., Hesselstrand, R., Saxne, T., DiMarzio, M., Wuttge, D., Agarwal, S. K., Reveille, J. D., & 25 others, 1 Jan 2014, In: New England journal of medicine. 370, 5, p. 433-443 11 p.Research output: Contribution to journal › Article › Academic › peer-review
313 Citations (Scopus)
Activities
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Single Cell Club
Mariateresa Coppola (Organiser), Mike de Kok (Organiser), Alsya Affandi (Organiser), Ernesto Rodriguez Camejo (Organiser), Febe van Maldegem (Organiser) & Lotte de Winde (Organiser)
Jan 2022 → …Activity: Participating in or organising an event › Organising a conference, workshop, ... › Academic
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A novel human dendritic cell subset expresses CD169 and cross-present vaccine to CD8+ T cells.
Alsya Affandi (Speaker)
16 Apr 2021Activity: Talk or presentation › Oral presentation › Academic
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Real Life Applications- Getting to know our customers and their research
Alsya Affandi (Speaker)
7 Apr 2021Activity: Talk or presentation › Invited talk › Academic
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British Society for Immunology (BSI) Virtual Conference
Alsya Affandi (Participant)
1 Dec 2020 → 2 Dec 2020Activity: Participating in or organising an event › Participating in a conference, workshop, ... › Academic
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Nanovaccine delivery to human CD169+ antigen-presenting cells in healthy and cancer patients
Alsya Affandi (Speaker)
18 Nov 2020Activity: Talk or presentation › Invited talk › Academic