Projects per year
Personal profile
Research interests
- Mechanism of coagulation
- Regulation of coagulation by the protein C system
- Regulation of coagulation by plasma protease inhibitors
- Mechanism of fibrinolysis
External positions
Professor, Sanquin
1 Feb 2014 → …
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Meijers J.C.M.: Biochemistry of hemostasis and thrombosis
Cunha, M., Plug, T., de Ronde, M., Meijers, J., Levels, J. & Peter, J.
1/01/2007 → …
Project: Research
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Hydrogen-deuterium exchange mass spectrometry highlights conformational changes induced by factor XI activation and binding of factor IX to factor XIa
Bar Barroeta, A., van Galen, J., Stroo, I., Marquart, J. A., Meijer, A. B. & Meijers, J. C. M., 2 Dec 2019, In: Journal of thrombosis and haemostasis. 17, 12, p. 2047-2055Research output: Contribution to journal › Article › Academic › peer-review
Open Access11 Citations (Scopus) -
Reversing direct factor Xa or thrombin inhibitors: Factor V addition to prothrombin complex concentrate is beneficial in vitro
Brinkman, H. J. M., Swieringa, F., Zuurveld, M., Veninga, A., Brouns, S. L. N., Heemskerk, J. W. M. & Meijers, J. C. M., 1 Mar 2022, In: Research and practice in thrombosis and haemostasis. 6, 3, e12699.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
A novel mutation in the F5 gene (factor V Amsterdam) associated with bleeding independent of factor V procoagulant function
Cunha, M. L. R., Bakhtiari, K., Peter, J., Marquart, J. A., Meijers, J. C. M. & Middeldorp, S., 2015, In: Blood. 125, 11, p. 1822-1825Research output: Contribution to journal › Article › Academic › peer-review
56 Citations (Scopus) -
Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects
Eerenberg, E. S., Kamphuisen, P. W., Sijpkens, M. K., Meijers, J. C., Buller, H. R. & Levi, M., 2011, In: Circulation. 124, 14, p. 1573-1579Research output: Contribution to journal › Article › Academic › peer-review
1299 Citations (Scopus) -
Basic science research opportunities in thrombosis and hemostasis: Communication from the SSC of the ISTH
Mutch, N. J., Walters, S., Gardiner, E. E., McCarty, O. J. T., de Meyer, S. F., Schroeder, V. & Meijers, J. C. M., Jun 2022, In: Journal of thrombosis and haemostasis. 20, 6, p. 1496-1506 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus)
Datasets
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Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) in complex with 2-guanidino-ethyl-mercaptosuccinic acid (GEMSA)
Marx, P. F. (Contributor), Brondijk, T. H. C. (Contributor), Plug, T. (Contributor), Romijn, R. A. (Contributor), Hemrika, W. (Contributor), Meijers, J. (Contributor) & Huizinga, E. G. (Contributor), Protein Data Bank (PDB), 1 Jul 2008
DOI: 10.2210/pdb3D67, https://www.wwpdb.org/pdb?id=pdb_00003d67
Dataset
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Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
Marx, P. F. (Contributor), Brondijk, T. H. C. (Contributor), Plug, T. (Contributor), Romijn, R. A. (Contributor), Hemrika, W. (Contributor), Meijers, J. (Contributor) & Huizinga, E. G. (Contributor), Protein Data Bank (PDB), 1 Jul 2008
DOI: 10.2210/pdb3D66, https://www.wwpdb.org/pdb?id=pdb_00003d66
Dataset
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Crystal structure of a T325I/T329I/H333Y/H335Q mutant of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI-IIYQ)
Marx, P. F. (Contributor), Brondijk, T. H. C. (Contributor), Plug, T. (Contributor), Romijn, R. A. (Contributor), Hemrika, W. (Contributor), Meijers, J. (Contributor) & Huizinga, E. G. (Contributor), Protein Data Bank (PDB), 1 Jul 2008
DOI: 10.2210/pdb3D68, https://www.wwpdb.org/pdb?id=pdb_00003d68
Dataset