Genetic and compound screens uncover factors modulating cancer cell response to indisulam

Pogacar, Z., Groot, K., Jochems, F., Dos Santos Dias, M., Mulero-Sánchez, A., Morris, B., Roosen, M., Wardak, L., de Conti, G., Velds, A., Lieftink, C., Thijssen, B., Beijersbergen, R. L., Bernards, R. & Leite de Oliveira, R., 1 Sept 2022, In: Life Science Alliance. 5, 9, e202101348.

Research output: Contribution to journal › Article › Academic › peer-review

cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis

Wang, L., Jin, H., Jochems, F., Wang, S., Lieftink, C., Martinez, I. M., de Conti, G., Edwards, F., de Oliveira, R. L., Schepers, A., Zhou, Y., Zheng, J., Wu, W., Zheng, X., Yuan, S., Ling, J., Jastrzebski, K., Santos Dias, M. D., Song, J-Y., Celie, P. N. H., & 6 othersYagita, H., Yao, M., Zhou, W., Beijersbergen, R. L., Qin, W. & Bernards, R., Nov 2022, In: Nature Cancer. 3, 11, p. 1284-1299 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity

Pogacar, Z., Johnson, J. L., Krenning, L., de Conti, G., Jochems, F., Lieftink, C., Velds, A., Wardak, L., Groot, K., Schepers, A., Wang, L., Song, J-Y., van de Ven, M., van Tellingen, O., Medema, R. H., Beijersbergen, R. L., Bernards, R. & Leite de Oliveira, R., Sept 2022, In: PLOS ONE. 17, 9 September, p. e0273182 e0273182.

Research output: Contribution to journal › Article › Academic › peer-review