TY - JOUR
T1 - A Neurobehavioral Intervention and Assessment Program in Very Low Birth Weight Infants: Outcome at 24 Months
AU - Koldewijn, Karen
AU - van Wassenaer, Aleid
AU - Wolf, Marie-Jeanne
AU - Meijssen, Dominique
AU - Houtzager, Bregje
AU - Beelen, Anita
AU - Kok, Joke
AU - Nollet, Frans
PY - 2010
Y1 - 2010
N2 - Objective To determine whether the Infant Behavioral Assessment and Intervention Program (IBAIP) improves development and behavior in very low birth weight (VLBW) infants at 24-month corrected age. Study design In a multicenter, randomized, controlled trial 86 infants received postdischarge intervention until 6-month corrected age. The intervention consisted of supporting infants' self-regulation and development, and facilitating sensitive parent-infant interactions; 90 control infants received regular care. At 6 months, positive intervention effects were found. At 24 months, development and behavior were evaluated with the Bayley Scales of Infant Development-II (BSID-II) and the Child Behavior Check List (CBCL). Results Eighty-three intervention and 78 control infants were available for follow-up. After adjustment for differences in perinatal characteristics, an intervention effect of 6.4 points (+/- standard error, 2.4) on the Psychomotor Developmental Index favored the intervention infants. Groups did not differ on the Mental Developmental Index, the Behavioral Rating Scale of the BSID-II, or on the CBCL. Subgroup analyses revealed improved motor as well as improved mental outcomes in intervention infants with bronchopulmonary dysplasia and with combined biological and social risk factors. Conclusions The IBAIP shows sustained motor improvement in VLBW infants until 2-year corrected age. (J Pediatr 2010;156:359-65)
AB - Objective To determine whether the Infant Behavioral Assessment and Intervention Program (IBAIP) improves development and behavior in very low birth weight (VLBW) infants at 24-month corrected age. Study design In a multicenter, randomized, controlled trial 86 infants received postdischarge intervention until 6-month corrected age. The intervention consisted of supporting infants' self-regulation and development, and facilitating sensitive parent-infant interactions; 90 control infants received regular care. At 6 months, positive intervention effects were found. At 24 months, development and behavior were evaluated with the Bayley Scales of Infant Development-II (BSID-II) and the Child Behavior Check List (CBCL). Results Eighty-three intervention and 78 control infants were available for follow-up. After adjustment for differences in perinatal characteristics, an intervention effect of 6.4 points (+/- standard error, 2.4) on the Psychomotor Developmental Index favored the intervention infants. Groups did not differ on the Mental Developmental Index, the Behavioral Rating Scale of the BSID-II, or on the CBCL. Subgroup analyses revealed improved motor as well as improved mental outcomes in intervention infants with bronchopulmonary dysplasia and with combined biological and social risk factors. Conclusions The IBAIP shows sustained motor improvement in VLBW infants until 2-year corrected age. (J Pediatr 2010;156:359-65)
U2 - https://doi.org/10.1016/j.jpeds.2009.09.009
DO - https://doi.org/10.1016/j.jpeds.2009.09.009
M3 - Article
C2 - 19880139
SN - 0022-3476
VL - 156
SP - 359
EP - 365
JO - Journal of pediatrics
JF - Journal of pediatrics
IS - 3
ER -