TY - JOUR
T1 - Ablation energies for focal treatment of prostate cancer
AU - Lodeizen, Olivia
AU - de Bruin, Martijn
AU - Eggener, Scott
AU - Crouzet, S. bastien
AU - Ghai, Sangeet
AU - Varkarakis, Ioannis
AU - Katz, Aaron
AU - Dominguez-Escrig, Jose Luis
AU - Pahernik, Sascha
AU - de Reijke, Theo
AU - de la Rosette, Jean
PY - 2019
Y1 - 2019
N2 - Context: In recent years, focal therapy has emerged as a treatment option for a selected group of men with localized prostate cancer. Cryotherapy and high-intensity focused ultrasound (HIFU) are the most investigated types of focal treatment with other options currently under evaluation. Objective: The objective of the study was to give a comprehensive overview of six available focal treatment options for prostate cancer with their rationale, delivery mechanism, and outcomes. Information acquisition: The SIU ICUD chapter on available Energies to Treat Prostate Cancer was used as a guide to describe the different technologies. For outcomes, a literature search was conducted using PubMed key words including focal therapy, HIFU, cryotherapy, irreversible electroporation, vascular-targeted photodynamic therapy, laser interstitial therapy, radiofrequency ablation, microwave therapy, and their synonyms in MeSH terms. Conclusion: Focal therapy appears to have encouraging outcomes on quality of life and urinary and erectile function. For oncological outcomes, it is challenging to fully interpret the outcomes due to heterogeneity in patient selection and short-term follow-up.
AB - Context: In recent years, focal therapy has emerged as a treatment option for a selected group of men with localized prostate cancer. Cryotherapy and high-intensity focused ultrasound (HIFU) are the most investigated types of focal treatment with other options currently under evaluation. Objective: The objective of the study was to give a comprehensive overview of six available focal treatment options for prostate cancer with their rationale, delivery mechanism, and outcomes. Information acquisition: The SIU ICUD chapter on available Energies to Treat Prostate Cancer was used as a guide to describe the different technologies. For outcomes, a literature search was conducted using PubMed key words including focal therapy, HIFU, cryotherapy, irreversible electroporation, vascular-targeted photodynamic therapy, laser interstitial therapy, radiofrequency ablation, microwave therapy, and their synonyms in MeSH terms. Conclusion: Focal therapy appears to have encouraging outcomes on quality of life and urinary and erectile function. For oncological outcomes, it is challenging to fully interpret the outcomes due to heterogeneity in patient selection and short-term follow-up.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85049011291&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/29943219
U2 - https://doi.org/10.1007/s00345-018-2364-x
DO - https://doi.org/10.1007/s00345-018-2364-x
M3 - Article
C2 - 29943219
SN - 0724-4983
VL - 37
SP - 409
EP - 418
JO - World Journal of Urology
JF - World Journal of Urology
IS - 3
ER -