Projects per year
Personal profile
Research interests
Currently, I'm involved in several projects, all using optics, photonics and light-tissue interaction to develop new diagnostic techniques and novel focal treatment modalities.
1) Digital 3D pathology, funded by ITEA
2) Aided diagnosis using i.e. machine learning and convolutional neural networks (CNN), funded by ITEA.
3) Imaging using contrast enhanced endoscopy, optical coherence tomography (OCT) and con-focal laser endomicroscopy (CLE) during diagnosis and surgical interventions, funded by ZonMW and cure for cancer (CFC).
4) Functional (in vivo) optical imaging of malignant and benign disease, funded by ZonMW and cure for cancer (CFC).
5) Design and development of new minimally invasive optical devices for in vivo use, funded by STW.
6) Focal therapy of malignancies using percutaneous laser ablation, funded by CFC and NWO-TTW.
7) Clinical Translation and intergration of novel optical technology.
specialisation
optics, photonics, imaging, focal therapy, urology, clinical translation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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van Leeuwen A.G.J.M.: Biomedical photonics for functional and molecular imaging
Achetib, N., Almasian, M., Bus, M., Gool, E., Hoveling, R., Jansen, I., Jansen, S., Jelvehgaran, P., Fagalde, K., Lucas, M., Muller, B., Peinado Cortes, L., Post, A., de Rond, L., Swaan, A., Wilk, L., Zhang, X., van Leeuwen, T., Aalders, M., Faber, D., de Bruin, M., Coumans, F., van Dam, A., van der Pol, E. & Riordan, A.
1/02/2007 → …
Project: Research
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de la Rosette J.J.M.C.H.: Minimal Invasive Urology and Oncological Urology
Baard, J., Buijs, M., Bus, M., Freund, J. E., Jansen, I., Legemate, J., Liem, E., Mannaerts, C., Muller, B., Postema, A., Sandbergen, L., Scheltema, M., Smeenge, M., van der Toom, E., Zondervan, P., Delarosette, J., Gerbrandy - Schreuders, L., Joosten, E., Kamphuis, G., Laguna Pes, M., Meißner, A., de Reijke, T., Wijkstra, H., Zondervan, P., de Bruin, M., Idzenga, T., Maas, I. & Wijdenes, M.
1/01/2006 → 13/06/2016
Project: Research
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Defining indocyanine green fluorescence to assess anastomotic perfusion during gastrointestinal surgery: systematic review
Slooter, M. D., Mansvelders, M. S. E., Bloemen, P. R., Gisbertz, S. S., Bemelman, W. A., Tanis, P. J., Hompes, R., van Berge Henegouwen, M. I. & de Bruin, D. M., 5 Mar 2021, In: BJS Open. 5, 2Research output: Contribution to journal › Article › Academic › peer-review
Open Access21 Citations (Scopus) -
Computed Tomography–Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study
Cernohorsky, P., Strackee, S. D., Streekstra, G. J., van den Wijngaard, J. P., Spaan, J. A. E., Siebes, M., van Leeuwen, T. G. & de Bruin, D. M., 2021, In: Cartilage. 13, Suppl. 1, p. 563S-507SResearch output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Three-dimensional histopathological reconstruction of bladder tumours
Jansen, I., Lucas, M., Savci-Heijink, C. D., Meijer, S. L., Liem, E. I. M. L., de Boer, O. J., van Leeuwen, T. G., Marquering, H. A. & de Bruin, D. M., 28 Mar 2019, In: Diagnostic pathology. 14, 1, p. 25 25.Research output: Contribution to journal › Article › Academic › peer-review
Open Access18 Citations (Scopus) -
Toward Automated In Vivo Bladder Tumor Stratification Using Confocal Laser Endomicroscopy
Lucas, M., Liem, E. I. M. L., Savci-Heijink, C. D., Freund, J. E., Marquering, H. A., van Leeuwen, T. G. & de Bruin, D. M., 2019, In: Journal of endourology / Endourological Society. 33, 11, p. 930-937Research output: Contribution to journal › Article › Academic › peer-review
12 Citations (Scopus) -
The First In Vivo Needle-Based Optical Coherence Tomography in Human Prostate: A Safety and Feasibility Study
Swaan, A., Mannaerts, C. K., Muller, B. G., van Kollenburg, R. A. A., Lucas, M., Savci-Heijink, C. D., van Leeuwen, T. G., de Reijke, T. M. & de Bruin, D. M., 1 Jul 2019, In: Lasers in surgery and medicine. 51, 5, p. 390-398Research output: Contribution to journal › Article › Academic › peer-review
Open Access9 Citations (Scopus)
Press/Media
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3DPathology - A digital pathology solution for more effective and efficient treatments
1/03/2021
1 Media contribution
Press/Media: Press / Media
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Hoe helpt technologie mensen met kanker, artrose en epilepsie?
8/02/2021
1 Media contribution
Press/Media: Press / Media
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Miniscule vuurtoren brengt niertumor in beeld
12/10/2018
1 Media contribution
Press/Media: Press / Media
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