Adverse childhood and recent negative life events: contrasting associations with cognitive decline in older persons

N.C.M. Korten; B.W.J.H. Penninx; A.M. Pot; D. Deeg; H.C. Comijs

doi:https://doi.org/10.1177/0891988714522696

Adverse childhood and recent negative life events: contrasting associations with cognitive decline in older persons

N.C.M. Korten, B.W.J.H. Penninx, A.M. Pot, D. Deeg, H.C. Comijs

Research output: Contribution to journal › Article › Academic › peer-review

38 Citations (Scopus)

Abstract

Objective: To examine whether persons who experienced adverse childhood events or recent negative life events have a worse cognitive performance and faster cognitive decline and the role of depression and apolipoprotein E-e4 in this relationship. Methods: The community-based sample consisted of 10-year follow-up data of 1312 persons participating in the Longitudinal Aging Study Amsterdam (age range 65-85 years). Results: Persons who experienced adverse childhood events showed a faster 10-year decline in processing speed but only when depressive symptoms were experienced. Persons with more recent negative life events showed slower processing speed at baseline but no faster decline. Conclusions: Childhood adversity may cause biological or psychological vulnerability, which is associated with both depressive symptoms and cognitive decline in later life. The accumulation of recent negative life events did not affect cognitive functioning over a longer time period. © The Author(s) 2014.

Original language	English
Pages (from-to)	128-138
Number of pages	12
Journal	Journal of geriatric psychiatry and neurology
Volume	27
Issue number	2
DOIs	https://doi.org/10.1177/0891988714522696
Publication status	Published - 2014

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https://doi.org/10.1177/0891988714522696

Cite this

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title = "Adverse childhood and recent negative life events: contrasting associations with cognitive decline in older persons",

abstract = "Objective: To examine whether persons who experienced adverse childhood events or recent negative life events have a worse cognitive performance and faster cognitive decline and the role of depression and apolipoprotein E-e4 in this relationship. Methods: The community-based sample consisted of 10-year follow-up data of 1312 persons participating in the Longitudinal Aging Study Amsterdam (age range 65-85 years). Results: Persons who experienced adverse childhood events showed a faster 10-year decline in processing speed but only when depressive symptoms were experienced. Persons with more recent negative life events showed slower processing speed at baseline but no faster decline. Conclusions: Childhood adversity may cause biological or psychological vulnerability, which is associated with both depressive symptoms and cognitive decline in later life. The accumulation of recent negative life events did not affect cognitive functioning over a longer time period. {\textcopyright} The Author(s) 2014.",

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T1 - Adverse childhood and recent negative life events: contrasting associations with cognitive decline in older persons

AU - Korten, N.C.M.

AU - Penninx, B.W.J.H.

AU - Pot, A.M.

AU - Deeg, D.

AU - Comijs, H.C.

PY - 2014

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N2 - Objective: To examine whether persons who experienced adverse childhood events or recent negative life events have a worse cognitive performance and faster cognitive decline and the role of depression and apolipoprotein E-e4 in this relationship. Methods: The community-based sample consisted of 10-year follow-up data of 1312 persons participating in the Longitudinal Aging Study Amsterdam (age range 65-85 years). Results: Persons who experienced adverse childhood events showed a faster 10-year decline in processing speed but only when depressive symptoms were experienced. Persons with more recent negative life events showed slower processing speed at baseline but no faster decline. Conclusions: Childhood adversity may cause biological or psychological vulnerability, which is associated with both depressive symptoms and cognitive decline in later life. The accumulation of recent negative life events did not affect cognitive functioning over a longer time period. © The Author(s) 2014.

AB - Objective: To examine whether persons who experienced adverse childhood events or recent negative life events have a worse cognitive performance and faster cognitive decline and the role of depression and apolipoprotein E-e4 in this relationship. Methods: The community-based sample consisted of 10-year follow-up data of 1312 persons participating in the Longitudinal Aging Study Amsterdam (age range 65-85 years). Results: Persons who experienced adverse childhood events showed a faster 10-year decline in processing speed but only when depressive symptoms were experienced. Persons with more recent negative life events showed slower processing speed at baseline but no faster decline. Conclusions: Childhood adversity may cause biological or psychological vulnerability, which is associated with both depressive symptoms and cognitive decline in later life. The accumulation of recent negative life events did not affect cognitive functioning over a longer time period. © The Author(s) 2014.

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