Arterial stiffness and Vitamin D levels: the Baltimore Longitudinal Study of Aging

F. Giallauria; Y. Milaneschi; T. Tanaka; M. Maggio; M. Canepa; P. Elango; C. Vigorito; E.G. Lakatta; L. Ferrucci; J. Strait

doi:https://doi.org/10.1210/jc.2012-1584

Arterial stiffness and Vitamin D levels: the Baltimore Longitudinal Study of Aging

F. Giallauria, Y. Milaneschi, T. Tanaka, M. Maggio, M. Canepa, P. Elango, C. Vigorito, E.G. Lakatta, L. Ferrucci, J. Strait

Psychiatry (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

75 Citations (Scopus)

Abstract

Context: The importance of vitamin D for bone health has long been acknowledged. Recent evidence suggests that vitamin D can also play a role in reducing the risk of several other diseases, including cardiovascular disease. Objective: The aim of this study is to test the hypothesis that 25-hydroxyvitamin D (25-OH D) is an independent cross-sectional correlate of central arterial stiffness in a normative aging study population. Design and Settings: We conducted a cross-sectional analysis. Subjects: We studied 1228 healthy volunteers (50% males; age, 70 ± 12 yr) of the Baltimore Longitudinal Study of Aging. Main Outcome Measures: We measured carotid-femoral pulse wave velocity (PWV) and 25-OH D levels. Results: We found a significant inverse association between PWV and 25-OH D levels (adjusted r

Original language	English
Pages (from-to)	3717-3723
Journal	Journal of clinical endocrinology and metabolism
Volume	97
Issue number	10
DOIs	https://doi.org/10.1210/jc.2012-1584
Publication status	Published - 2012

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https://doi.org/10.1210/jc.2012-1584

Cite this

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title = "Arterial stiffness and Vitamin D levels: the Baltimore Longitudinal Study of Aging",

abstract = "Context: The importance of vitamin D for bone health has long been acknowledged. Recent evidence suggests that vitamin D can also play a role in reducing the risk of several other diseases, including cardiovascular disease. Objective: The aim of this study is to test the hypothesis that 25-hydroxyvitamin D (25-OH D) is an independent cross-sectional correlate of central arterial stiffness in a normative aging study population. Design and Settings: We conducted a cross-sectional analysis. Subjects: We studied 1228 healthy volunteers (50% males; age, 70 ± 12 yr) of the Baltimore Longitudinal Study of Aging. Main Outcome Measures: We measured carotid-femoral pulse wave velocity (PWV) and 25-OH D levels. Results: We found a significant inverse association between PWV and 25-OH D levels (adjusted r",

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AU - Giallauria, F.

AU - Milaneschi, Y.

AU - Tanaka, T.

AU - Maggio, M.

AU - Canepa, M.

AU - Elango, P.

AU - Vigorito, C.

AU - Lakatta, E.G.

AU - Ferrucci, L.

AU - Strait, J.

PY - 2012

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AB - Context: The importance of vitamin D for bone health has long been acknowledged. Recent evidence suggests that vitamin D can also play a role in reducing the risk of several other diseases, including cardiovascular disease. Objective: The aim of this study is to test the hypothesis that 25-hydroxyvitamin D (25-OH D) is an independent cross-sectional correlate of central arterial stiffness in a normative aging study population. Design and Settings: We conducted a cross-sectional analysis. Subjects: We studied 1228 healthy volunteers (50% males; age, 70 ± 12 yr) of the Baltimore Longitudinal Study of Aging. Main Outcome Measures: We measured carotid-femoral pulse wave velocity (PWV) and 25-OH D levels. Results: We found a significant inverse association between PWV and 25-OH D levels (adjusted r

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