TY - JOUR
T1 - Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters
AU - Schade, Rogier P.
AU - Schinkel, Janke
AU - Visser, Leo G.
AU - van Dijk, J. Marc C.
AU - Voormolen, Joan H. C.
AU - Kuijper, Ed J.
PY - 2005/2/1
Y1 - 2005/2/1
N2 - In the present study the authors compared the incidence and risk factors for external drainage-related bacterial meningitis (ED-BM) by using ventricular and lumbar catheters. A cohort of 230 consecutive patients with ED was evaluated. Cerebrospinal fluid samples were obtained daily for microbiological culture, and ED-BM was defined based on culture results in combination with clinical symptoms. The incidence of ED-BM was 7% in lumbar and 15% in ventricular drains. Independent risk factors included site leakage, drain blockage, and most importantly duration of ED. Despite a higher infection rate, ventricular catheters did not have a significant higher risk of infection after correcting for duration of drainage. Analysis of data in the present study showed that the incidence of ED-associated death is low (0.45%) in patients who do not receive continuous antibiotic prophylaxis during ED
AB - In the present study the authors compared the incidence and risk factors for external drainage-related bacterial meningitis (ED-BM) by using ventricular and lumbar catheters. A cohort of 230 consecutive patients with ED was evaluated. Cerebrospinal fluid samples were obtained daily for microbiological culture, and ED-BM was defined based on culture results in combination with clinical symptoms. The incidence of ED-BM was 7% in lumbar and 15% in ventricular drains. Independent risk factors included site leakage, drain blockage, and most importantly duration of ED. Despite a higher infection rate, ventricular catheters did not have a significant higher risk of infection after correcting for duration of drainage. Analysis of data in the present study showed that the incidence of ED-associated death is low (0.45%) in patients who do not receive continuous antibiotic prophylaxis during ED
KW - Central nervous system infection
KW - Cerebrospinal fluid drainage
KW - Lumbar subarachnoid catheter
KW - Risk factor
KW - Ventriculostomy catheter
UR - http://www.scopus.com/inward/record.url?scp=14844309413&partnerID=8YFLogxK
U2 - https://doi.org/10.3171/jns.2005.102.2.0229
DO - https://doi.org/10.3171/jns.2005.102.2.0229
M3 - Article
C2 - 15739549
SN - 0022-3085
VL - 102
SP - 229
EP - 234
JO - Journal of neurosurgery
JF - Journal of neurosurgery
IS - 2
ER -