TY - JOUR
T1 - Borrelia miyamotoi: a widespread tick-borne relapsing fever spirochete
AU - Wagemakers, Alex
AU - Staarink, Pieter J.
AU - Sprong, Hein
AU - Hovius, Joppe W. R.
PY - 2015
Y1 - 2015
N2 - Borrelia miyamotoi is a relapsing fever spirochete that has only recently been identified as a human pathogen. Borrelia miyamotoi is genetically and ecologically distinct from Borrelia burgdorferi sensu lato, while both are present in Ixodes ticks. Over 50 patients with an acute febrile illness have been described with a B. miyamotoi infection, and two infected immunocompromised patients developed a meningoencephalitis. Seroprevalence studies indicate exposure in the general population and in specific risk groups, such as patients initially suspected of having human granulocytic anaplasmosis. Here, we review the available literature on B. miyamotoi, describing its presence in ticks, reservoir hosts, and humans, and discussing its potential impact on public health
AB - Borrelia miyamotoi is a relapsing fever spirochete that has only recently been identified as a human pathogen. Borrelia miyamotoi is genetically and ecologically distinct from Borrelia burgdorferi sensu lato, while both are present in Ixodes ticks. Over 50 patients with an acute febrile illness have been described with a B. miyamotoi infection, and two infected immunocompromised patients developed a meningoencephalitis. Seroprevalence studies indicate exposure in the general population and in specific risk groups, such as patients initially suspected of having human granulocytic anaplasmosis. Here, we review the available literature on B. miyamotoi, describing its presence in ticks, reservoir hosts, and humans, and discussing its potential impact on public health
U2 - https://doi.org/10.1016/j.pt.2015.03.008
DO - https://doi.org/10.1016/j.pt.2015.03.008
M3 - Review article
C2 - 25892254
SN - 1471-4922
VL - 31
SP - 260
EP - 269
JO - Trends in parasitology
JF - Trends in parasitology
IS - 6
ER -