Coccidioidomycosis Infection of a Total Knee Arthroplasty in a Nonendemic Region

Shennah Austen; Walter van der Weegen; Cees M. Verduin; Marc van der Valk; Henk J. Hoekstra

doi:https://doi.org/10.1016/j.arth.2012.05.006

Coccidioidomycosis Infection of a Total Knee Arthroplasty in a Nonendemic Region

Shennah Austen, Walter van der Weegen, Cees M. Verduin, Marc van der Valk, Henk J. Hoekstra

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

Abstract

Fungal prosthetic joint infections are rare and difficult to treat. There is an ongoing discussion about the type and duration of antifungal treatment and the necessity of prosthesis removal. We report the first European case of an infected total knee arthroplasty with Coccidioides immitis. Treatment consisted of lifelong treatment with oral fluconazole at a dose of 400 mg/d, without total knee arthroplasty removal. After 6 months, the initial complaints of pain and swelling were completely resolved. This case report clearly states that a travel history and culturing for fungi are helpful in patients with persisting complaints after joint arthroplasty. (C) 2013 Elsevier Inc. All rights reserved

Original language	English
Pages (from-to)	375.e13-375.e15
Journal	Journal of Arthroplasty
Volume	28
Issue number	2
DOIs	https://doi.org/10.1016/j.arth.2012.05.006
Publication status	Published - 2013

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https://doi.org/10.1016/j.arth.2012.05.006

Cite this

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title = "Coccidioidomycosis Infection of a Total Knee Arthroplasty in a Nonendemic Region",

abstract = "Fungal prosthetic joint infections are rare and difficult to treat. There is an ongoing discussion about the type and duration of antifungal treatment and the necessity of prosthesis removal. We report the first European case of an infected total knee arthroplasty with Coccidioides immitis. Treatment consisted of lifelong treatment with oral fluconazole at a dose of 400 mg/d, without total knee arthroplasty removal. After 6 months, the initial complaints of pain and swelling were completely resolved. This case report clearly states that a travel history and culturing for fungi are helpful in patients with persisting complaints after joint arthroplasty. (C) 2013 Elsevier Inc. All rights reserved",

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AU - Hoekstra, Henk J.

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AB - Fungal prosthetic joint infections are rare and difficult to treat. There is an ongoing discussion about the type and duration of antifungal treatment and the necessity of prosthesis removal. We report the first European case of an infected total knee arthroplasty with Coccidioides immitis. Treatment consisted of lifelong treatment with oral fluconazole at a dose of 400 mg/d, without total knee arthroplasty removal. After 6 months, the initial complaints of pain and swelling were completely resolved. This case report clearly states that a travel history and culturing for fungi are helpful in patients with persisting complaints after joint arthroplasty. (C) 2013 Elsevier Inc. All rights reserved

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