Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter

Anita Chandra; Fang Zhang; Kimberly C Gilmour; David Webster; Vincent Plagnol; Dinakantha S Kumararatne; Siobhan O Burns; Sergey Nejentsev; Adrian J Thrasher

doi:https://doi.org/10.1016/j.jaci.2015.08.049

Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter

Anita Chandra, Fang Zhang, Kimberly C Gilmour, David Webster, Vincent Plagnol, Dinakantha S Kumararatne, Siobhan O Burns, Sergey Nejentsev, Adrian J Thrasher

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Original language	English
Pages (from-to)	940-2.e4
Journal	Journal of allergy and clinical immunology
Volume	137
Issue number	3
DOIs	https://doi.org/10.1016/j.jaci.2015.08.049
Publication status	Published - Mar 2016
Externally published	Yes

Keywords

Adult
Binding Sites
Child, Preschool
Common Variable Immunodeficiency/diagnosis
Humans
Interleukin Receptor Common gamma Subunit/genetics
Killer Cells, Natural/metabolism
Lymphopenia/diagnosis
Male
Mutation
Promoter Regions, Genetic
Protein Binding
Proto-Oncogene Proteins c-ets/metabolism

Access to Document

https://doi.org/10.1016/j.jaci.2015.08.049

Cite this

Chandra, A., Zhang, F., Gilmour, K. C., Webster, D., Plagnol, V., Kumararatne, D. S., Burns, S. O., Nejentsev, S., & Thrasher, A. J. (2016). Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter. Journal of allergy and clinical immunology, 137(3), 940-2.e4. https://doi.org/10.1016/j.jaci.2015.08.049

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keywords = "Adult, Binding Sites, Child, Preschool, Common Variable Immunodeficiency/diagnosis, Humans, Interleukin Receptor Common gamma Subunit/genetics, Killer Cells, Natural/metabolism, Lymphopenia/diagnosis, Male, Mutation, Promoter Regions, Genetic, Protein Binding, Proto-Oncogene Proteins c-ets/metabolism",

author = "Anita Chandra and Fang Zhang and Gilmour, {Kimberly C} and David Webster and Vincent Plagnol and Kumararatne, {Dinakantha S} and Burns, {Siobhan O} and Sergey Nejentsev and Thrasher, {Adrian J}",

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language = "English",

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Chandra, A, Zhang, F, Gilmour, KC, Webster, D, Plagnol, V, Kumararatne, DS, Burns, SO, Nejentsev, S & Thrasher, AJ 2016, 'Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter', Journal of allergy and clinical immunology, vol. 137, no. 3, pp. 940-2.e4. https://doi.org/10.1016/j.jaci.2015.08.049

Common variable immunodeficiency and natural killer cell lymphopenia caused by Ets-binding site mutation in the IL-2 receptor γ (IL2RG) gene promoter. / Chandra, Anita; Zhang, Fang; Gilmour, Kimberly C et al.
In: Journal of allergy and clinical immunology, Vol. 137, No. 3, 03.2016, p. 940-2.e4.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Chandra, Anita

AU - Zhang, Fang

AU - Gilmour, Kimberly C

AU - Webster, David

AU - Plagnol, Vincent

AU - Kumararatne, Dinakantha S

AU - Burns, Siobhan O

AU - Nejentsev, Sergey

AU - Thrasher, Adrian J

PY - 2016/3

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KW - Binding Sites

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KW - Common Variable Immunodeficiency/diagnosis

KW - Humans

KW - Interleukin Receptor Common gamma Subunit/genetics

KW - Killer Cells, Natural/metabolism

KW - Lymphopenia/diagnosis

KW - Male

KW - Mutation

KW - Promoter Regions, Genetic

KW - Protein Binding

KW - Proto-Oncogene Proteins c-ets/metabolism

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DO - https://doi.org/10.1016/j.jaci.2015.08.049

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SP - 940-2.e4

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