TY - JOUR
T1 - Consensus criteria for chronic rhinosinusitis disease control
T2 - an international Delphi Study*
AU - Sedaghat, Ahmad R.
AU - Fokkens, Wytske J.
AU - Lund, Valerie J.
AU - Hellings, Peter W.
AU - Kern, Robert C.
AU - Reitsma, Sietze
AU - Toppila-Salmi, Sanna
AU - Bernal-Sprekelsen, Manuel
AU - Mullol, Joaquim
AU - Gevaert, Philippe
AU - Teeling, Thijs
AU - Alobid, Isam
AU - Anselmo-Lima, Wilma T.
AU - Baroody, Fuad M.
AU - Cervin, Anders
AU - Cohen, Noam A.
AU - Constantinidis, Jannis
AU - Gabory, Ludovic De
AU - Desrosiers, Martin
AU - Harvey, Richard J.
AU - Kalogjera, Livije
AU - Knill, Andrew
AU - Landis, Basile N.
AU - Meco, Cem
AU - Philpott, Carl M.
AU - Ryan, Dermot
AU - Schlosser, Rodney J.
AU - Senior, Brent A.
AU - Smith, Timothy L.
AU - Tomazic, Peter V.
AU - Zhang, Luo
AU - Hopkins, Claire
PY - 2023
Y1 - 2023
N2 - Background: Chronic rhinosinusitis (CRS) disease control is a global metric of disease status for CRS. While there is broad acceptance that it is an important treatment goal, there has been inconsistency in the criteria used to define CRS control. The objective of this study was to identify and develop consensus around essential criteria for assessment of CRS disease control. Methods: Modified Delphi methodology consisting of three rounds to review a list of 24 possible CRS control criteria developed by a 12-person steering committee. The core authorship of the multidisciplinary EPOS 2020 guidelines was invited to participate. Results: Thirty-two individuals accepted the invitation to participate and there was no dropout of participants throughout the entire study (3 rounds). Consensus essential criteria for assessment of CRS control were: overall symptom severity, need for CRS-related systemic corticosteroids in the prior 6 months, severity of nasal obstruction, and patient-reported CRS control. Near-consensus items were: nasal endoscopy findings, severity of smell loss, overall quality of life, impairment of normal activities and severity of nasal discharge. Participants’ comments provided insights into caveats of, and disagreements related to, near-consensus items. Conclusions: Overall symptom severity, use of CRS-related systemic corticosteroids, severity of nasal obstruction, and patient-reported CRS control are widely agreed upon essential criteria for assessment of CRS disease control. Consideration of near-consensus items to assess CRS control should be implemented with their intrinsic caveats in mind. These identified consensus CRS control criteria, together with evidence-based support, will provide a foundation upon which CRS control criteria with wide-spread acceptance can be developed.
AB - Background: Chronic rhinosinusitis (CRS) disease control is a global metric of disease status for CRS. While there is broad acceptance that it is an important treatment goal, there has been inconsistency in the criteria used to define CRS control. The objective of this study was to identify and develop consensus around essential criteria for assessment of CRS disease control. Methods: Modified Delphi methodology consisting of three rounds to review a list of 24 possible CRS control criteria developed by a 12-person steering committee. The core authorship of the multidisciplinary EPOS 2020 guidelines was invited to participate. Results: Thirty-two individuals accepted the invitation to participate and there was no dropout of participants throughout the entire study (3 rounds). Consensus essential criteria for assessment of CRS control were: overall symptom severity, need for CRS-related systemic corticosteroids in the prior 6 months, severity of nasal obstruction, and patient-reported CRS control. Near-consensus items were: nasal endoscopy findings, severity of smell loss, overall quality of life, impairment of normal activities and severity of nasal discharge. Participants’ comments provided insights into caveats of, and disagreements related to, near-consensus items. Conclusions: Overall symptom severity, use of CRS-related systemic corticosteroids, severity of nasal obstruction, and patient-reported CRS control are widely agreed upon essential criteria for assessment of CRS disease control. Consideration of near-consensus items to assess CRS control should be implemented with their intrinsic caveats in mind. These identified consensus CRS control criteria, together with evidence-based support, will provide a foundation upon which CRS control criteria with wide-spread acceptance can be developed.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85178511980&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/37804121
U2 - 10.4193/Rhin23.335
DO - 10.4193/Rhin23.335
M3 - Article
C2 - 37804121
SN - 0300-0729
VL - 61
SP - 519
EP - 530
JO - Rhinology
JF - Rhinology
IS - 6
ER -