Deciphering cellular decluttering: The impact of autophagy mechanisms in host-virus immune interactions

A.P.M. Cloherty

Deciphering cellular decluttering: The impact of autophagy mechanisms in host-virus immune interactions

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

Within this thesis, we connect in-depth molecular investigation of innate intracellular immune mechanisms with the practical study of repurposing host-targeting pharmaceuticals for antiviral defense. These dual aims are underpinned by the use of human-relevant, animal-free models. Throughout, we focus on autophagy, a host system of ‘decluttering’ and defense in which

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	Ribeiro, Carla, Supervisor Schreurs, Renee, Co-supervisor Ribeiro, C.M.S., Supervisor, External person
Award date	16 Nov 2023
Publication status	Published - 2023

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title = "Deciphering cellular decluttering: The impact of autophagy mechanisms in host-virus immune interactions",

abstract = "Within this thesis, we connect in-depth molecular investigation of innate intracellular immune mechanisms with the practical study of repurposing host-targeting pharmaceuticals for antiviral defense. These dual aims are underpinned by the use of human-relevant, animal-free models. Throughout, we focus on autophagy, a host system of {\textquoteleft}decluttering{\textquoteright} and defense in which",

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AB - Within this thesis, we connect in-depth molecular investigation of innate intracellular immune mechanisms with the practical study of repurposing host-targeting pharmaceuticals for antiviral defense. These dual aims are underpinned by the use of human-relevant, animal-free models. Throughout, we focus on autophagy, a host system of ‘decluttering’ and defense in which

UR - https://pure.uva.nl/ws/files/144608489/Licence_Agreement_co-signed_.pdf

M3 - Phd-Thesis - Research and graduation internal

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Deciphering cellular decluttering: The impact of autophagy mechanisms in host-virus immune interactions

Abstract

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