TY - JOUR
T1 - Development of the Arm Function in Multiple Sclerosis Questionnaire-Short Form (AMSQ-SF)
T2 - A static 10-item version
AU - Luijten, Michiel A.J.
AU - Eekhout, Iris
AU - D’Hooghe, Marie
AU - Uitdehaag, Bernard M.J.
AU - Mokkink, Lidwine B.
N1 - Publisher Copyright: © The Author(s), 2018.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Background: Assessing arm and hand function of multiple sclerosis (MS) patients is important as impaired functioning may impact daily activities and reduce quality of life. Objective: A short-form of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ), a recently developed patient-reported outcome measure containing 31 items, is developed to allow non-adaptive application. Methods: Complete data from 690 patients with MS, recruited via outpatient clinics, a residential center or via a Dutch website aimed at MS patients, were included in the analyses. A graded response model was fit to these data to estimate item response theory (IRT) parameters, which were used to perform post hoc computerized adaptive test (CAT) simulations with a cutoff standard error of measurement (SEM) of 0.32. The optimal test length was determined by the correlation between the static short-form and full-length theta, the mean SEM, and the amount of patients reaching a satisfactory SEM in CAT simulations. Results and Conclusion: Based on five selection criteria (i.e. discrimination parameters, total information, times selected in CAT simulations, raw item means, and item content), 10 items were selected for inclusion in the short-form. The score on the final 10-item short-form correlated strongly with the full-length AMSQ and provided reliable ability estimations, indicating its usefulness instrument in research and clinical settings.
AB - Background: Assessing arm and hand function of multiple sclerosis (MS) patients is important as impaired functioning may impact daily activities and reduce quality of life. Objective: A short-form of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ), a recently developed patient-reported outcome measure containing 31 items, is developed to allow non-adaptive application. Methods: Complete data from 690 patients with MS, recruited via outpatient clinics, a residential center or via a Dutch website aimed at MS patients, were included in the analyses. A graded response model was fit to these data to estimate item response theory (IRT) parameters, which were used to perform post hoc computerized adaptive test (CAT) simulations with a cutoff standard error of measurement (SEM) of 0.32. The optimal test length was determined by the correlation between the static short-form and full-length theta, the mean SEM, and the amount of patients reaching a satisfactory SEM in CAT simulations. Results and Conclusion: Based on five selection criteria (i.e. discrimination parameters, total information, times selected in CAT simulations, raw item means, and item content), 10 items were selected for inclusion in the short-form. The score on the final 10-item short-form correlated strongly with the full-length AMSQ and provided reliable ability estimations, indicating its usefulness instrument in research and clinical settings.
KW - Arm Function in Multiple Sclerosis Questionnaire
KW - computerized adaptive testing simulations
KW - item response model
KW - multiple sclerosis
KW - psychometrics
UR - http://www.scopus.com/inward/record.url?scp=85058138461&partnerID=8YFLogxK
U2 - https://doi.org/10.1177/1352458518808197
DO - https://doi.org/10.1177/1352458518808197
M3 - Article
C2 - 30411658
SN - 1352-4585
VL - 24
SP - 1892
EP - 1901
JO - MULTIPLE SCLEROSIS JOURNAL
JF - MULTIPLE SCLEROSIS JOURNAL
IS - 14
ER -