Examination of the Role of Galectins and Galectin Inhibitors in Endothelial Cell Biology

Kitty C.M. Castricum, Victor L.J.L. Thijssen

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review


The growth of new blood vessels is a key event in many (patho) physiological processes, including embryogenesis, wound healing, inflammatory diseases, and cancer. Neovascularization requires different, well-coordinated actions of endothelial cells, i.e., the cells lining the luminal side of all blood vessels. Galectins are involved in several of these activities. In this chapter, we describe methods to study galectins in three key functions of endothelial cells during angiogenesis, i.e., endothelial cell migration, endothelial cell sprouting, and endothelial cell network formation.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Number of pages8
Publication statusPublished - 2022

Publication series

NameMethods in Molecular Biology


  • Angiogenesis
  • Endothelial cell
  • Galectin
  • Migration
  • Network formation
  • Sprouting

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