TY - JOUR
T1 - Expression of muscle segment homeobox genes in the developing myocardium
AU - Boogerd, Cornelis J. J.
AU - Moorman, Antoon F. M.
AU - Barnett, Phil
PY - 2010
Y1 - 2010
N2 - Msx1 and Msx2 are essential for the development of many organs. In the heart, they act redundantly in development of the cardiac cushions. Additionally, Msx2 is expressed in the developing conduction system. However, the exact expression of Msx1 has not been established. We show that Msx1 is expressed in the cardiac cushions, but not in the myocardium. In Msx2-null mice, Msx1 is not ectopically expressed in the myocardium. The absence of myocardial defects in the Msx2 knock-out can therefore not be attributed to a redundant action of Msx1 in the myocardium
AB - Msx1 and Msx2 are essential for the development of many organs. In the heart, they act redundantly in development of the cardiac cushions. Additionally, Msx2 is expressed in the developing conduction system. However, the exact expression of Msx1 has not been established. We show that Msx1 is expressed in the cardiac cushions, but not in the myocardium. In Msx2-null mice, Msx1 is not ectopically expressed in the myocardium. The absence of myocardial defects in the Msx2 knock-out can therefore not be attributed to a redundant action of Msx1 in the myocardium
U2 - https://doi.org/10.1002/ar.21112
DO - https://doi.org/10.1002/ar.21112
M3 - Article
C2 - 20225205
SN - 1932-8486
VL - 293
SP - 998
EP - 1001
JO - Anatomical record (Hoboken, N.J.
JF - Anatomical record (Hoboken, N.J.
IS - 6
ER -