TY - JOUR
T1 - Identification of a genetic subcluster of HIV type 1 subtype C (C') widespread in Ethiopia
AU - Abebe, A.
AU - Pollakis, G.
AU - Fontanet, A. L.
AU - Fisseha, B.
AU - Tegbaru, B.
AU - Kliphuis, A.
AU - Tesfaye, G.
AU - Negassa, H.
AU - Cornelissen, M.
AU - Goudsmit, J.
AU - Rinke de Wit, T. F.
PY - 2000
Y1 - 2000
N2 - Others and we have previously shown that subtype C is the predominant HIV-1 subtype and the major cause of AIDS in Ethiopia. The present study shows that subtype C in Ethiopia has a genetic subcluster, designated C', has not increased in frequency, or spread geographically, over the period 1988 (%C' = 23/53) to 1996-1997 (%C' = 26/50). There is no association of the HIV-1 subtype C or subcluster C' with geographic location, time of sample collection, or risk group in Ethiopia. Of 105 randomly collected samples representing 7 different towns in Ethiopia, all but 2 (1 subtype A from Addis Ababa, 1997 and 1 subtype D from Dessie, 1996) belong to subtype C
AB - Others and we have previously shown that subtype C is the predominant HIV-1 subtype and the major cause of AIDS in Ethiopia. The present study shows that subtype C in Ethiopia has a genetic subcluster, designated C', has not increased in frequency, or spread geographically, over the period 1988 (%C' = 23/53) to 1996-1997 (%C' = 26/50). There is no association of the HIV-1 subtype C or subcluster C' with geographic location, time of sample collection, or risk group in Ethiopia. Of 105 randomly collected samples representing 7 different towns in Ethiopia, all but 2 (1 subtype A from Addis Ababa, 1997 and 1 subtype D from Dessie, 1996) belong to subtype C
U2 - https://doi.org/10.1089/08892220050195865
DO - https://doi.org/10.1089/08892220050195865
M3 - Article
C2 - 11118076
SN - 0889-2229
VL - 16
SP - 1909
EP - 1914
JO - AIDS Research and Human Retroviruses
JF - AIDS Research and Human Retroviruses
IS - 17
ER -