Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma

Paul W G Elbers, Antonius J. Craenen, Antoine Driessen, Marco C. Stehouwer, Luuk Munsterman, Miranda Prins, Mat van Iterson, Peter Bruins, Can Ince

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The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR.

Original languageEnglish
Pages (from-to)123-125
Number of pages3
Issue number1
Publication statusPublished - 1 Jan 2010


  • Cardiopulmonary bypass
  • Cardiopulmonary resuscitation
  • Extracorporeal circulation
  • Hypothermia
  • Mechanical compression/decompression
  • Microcirculation
  • Sidestream dark field imaging
  • Submersion
  • Trauma

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