Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma

Paul W G Elbers; Antonius J. Craenen; Antoine Driessen; Marco C. Stehouwer; Luuk Munsterman; Miranda Prins; Mat van Iterson; Peter Bruins; Can Ince

doi:https://doi.org/10.1016/j.resuscitation.2009.09.032

Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma

Paul W G Elbers, Antonius J. Craenen, Antoine Driessen, Marco C. Stehouwer, Luuk Munsterman, Miranda Prins, Mat van Iterson, Peter Bruins, Can Ince

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR.

Original language	English
Pages (from-to)	123-125
Number of pages	3
Journal	Resuscitation
Volume	81
Issue number	1
DOIs	https://doi.org/10.1016/j.resuscitation.2009.09.032
Publication status	Published - 1 Jan 2010

Keywords

Cardiopulmonary bypass
Cardiopulmonary resuscitation
Extracorporeal circulation
Hypothermia
Mechanical compression/decompression
Microcirculation
Sidestream dark field imaging
Submersion
Trauma

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Cite this

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title = "Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma",

abstract = "The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR.",

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AU - Stehouwer, Marco C.

AU - Munsterman, Luuk

AU - Prins, Miranda

AU - van Iterson, Mat

AU - Bruins, Peter

AU - Ince, Can

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KW - Mechanical compression/decompression

KW - Microcirculation

KW - Sidestream dark field imaging

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Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma

Abstract

Keywords

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