Influences on PET Quantification and Interpretation

Julian M. M. Rogasch; Frank Hofheinz; Lutz van Heek; Conrad-Amadeus Voltin; Ronald Boellaard; Carsten Kobe

doi:https://doi.org/10.3390/diagnostics12020451

Influences on PET Quantification and Interpretation

Julian M. M. Rogasch, Frank Hofheinz, Lutz van Heek, Conrad-Amadeus Voltin, Ronald Boellaard, Carsten Kobe

Research output: Contribution to journal › Review article › Academic › peer-review

11 Citations (Scopus)

Abstract

Various factors have been identified that influence quantitative accuracy and image interpretation in positron emission tomography (PET). Through the continuous introduction of new PET technology—both imaging hardware and reconstruction software—into clinical care, we now find ourselves in a transition period in which traditional and new technologies coexist. The effects on the clinical value of PET imaging and its interpretation in routine clinical practice require careful reevaluation. In this review, we provide a comprehensive summary of important factors influencing quantification and interpretation with a focus on recent developments in PET technology. Finally, we discuss the relationship between quantitative accuracy and subjective image interpretation.

Original language	English
Article number	451
Journal	Diagnostics (Basel, Switzerland)
Volume	12
Issue number	2
DOIs	https://doi.org/10.3390/diagnostics12020451
Publication status	Published - 1 Feb 2022

Keywords

Contrast recovery
Image interpretation
Image quality
Positron emission tomography
Quantitative accuracy
Signal-to-noise ratio

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https://doi.org/10.3390/diagnostics12020451

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abstract = "Various factors have been identified that influence quantitative accuracy and image interpretation in positron emission tomography (PET). Through the continuous introduction of new PET technology—both imaging hardware and reconstruction software—into clinical care, we now find ourselves in a transition period in which traditional and new technologies coexist. The effects on the clinical value of PET imaging and its interpretation in routine clinical practice require careful reevaluation. In this review, we provide a comprehensive summary of important factors influencing quantification and interpretation with a focus on recent developments in PET technology. Finally, we discuss the relationship between quantitative accuracy and subjective image interpretation.",

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AU - Rogasch, Julian M. M.

AU - Hofheinz, Frank

AU - van Heek, Lutz

AU - Voltin, Conrad-Amadeus

AU - Boellaard, Ronald

AU - Kobe, Carsten

PY - 2022/2/1

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N2 - Various factors have been identified that influence quantitative accuracy and image interpretation in positron emission tomography (PET). Through the continuous introduction of new PET technology—both imaging hardware and reconstruction software—into clinical care, we now find ourselves in a transition period in which traditional and new technologies coexist. The effects on the clinical value of PET imaging and its interpretation in routine clinical practice require careful reevaluation. In this review, we provide a comprehensive summary of important factors influencing quantification and interpretation with a focus on recent developments in PET technology. Finally, we discuss the relationship between quantitative accuracy and subjective image interpretation.

AB - Various factors have been identified that influence quantitative accuracy and image interpretation in positron emission tomography (PET). Through the continuous introduction of new PET technology—both imaging hardware and reconstruction software—into clinical care, we now find ourselves in a transition period in which traditional and new technologies coexist. The effects on the clinical value of PET imaging and its interpretation in routine clinical practice require careful reevaluation. In this review, we provide a comprehensive summary of important factors influencing quantification and interpretation with a focus on recent developments in PET technology. Finally, we discuss the relationship between quantitative accuracy and subjective image interpretation.

KW - Contrast recovery

KW - Image interpretation

KW - Image quality

KW - Positron emission tomography

KW - Quantitative accuracy

KW - Signal-to-noise ratio

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DO - https://doi.org/10.3390/diagnostics12020451

M3 - Review article

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VL - 12

JO - Diagnostics (Basel, Switzerland)

JF - Diagnostics (Basel, Switzerland)

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Influences on PET Quantification and Interpretation

Abstract

Keywords

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