Met HIV samenhangend non-Hodgkin-lymfoom bij 45 patiënten; een retrospectieve analyse

M. J. Kersten; M. J. Mertens; S. T. Pals; P. Reiss; M. H. van Oers

Met HIV samenhangend non-Hodgkin-lymfoom bij 45 patiënten; een retrospectieve analyse

M. J. Kersten, M. J. Mertens, S. T. Pals, P. Reiss, M. H. van Oers

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Abstract

Non-Hodgkin lymphoma is seen in approximately 5% of patients with AIDS. In recent years, the incidence has increased due to an extension of the average lifespan of HIV-infected individuals. In this article we describe the histological and clinical features of 45 patients with HIV-related non-Hodgkin lymphoma seen at the Academic Medical Centre between 1984 and 1991. There were 43 men and 2 women with a median age of 40 years. Most patients had high-grade B-cell lymphoma; 85% had extranodal sites. Prognosis was poor: overall median survival was only 3.8 months. Twelve patients were treated with 3 or more courses of chemotherapy: their median survival was 8 months. In 7 of 12 patients a complete remission was obtained; their median survival was 18 months. A history of AIDS was a poor prognostic factor

Original language	Dutch
Pages (from-to)	1396-1400
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	137
Issue number	28
Publication status	Published - 1993

Cite this

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title = "Met HIV samenhangend non-Hodgkin-lymfoom bij 45 pati{\"e}nten; een retrospectieve analyse",

abstract = "Non-Hodgkin lymphoma is seen in approximately 5% of patients with AIDS. In recent years, the incidence has increased due to an extension of the average lifespan of HIV-infected individuals. In this article we describe the histological and clinical features of 45 patients with HIV-related non-Hodgkin lymphoma seen at the Academic Medical Centre between 1984 and 1991. There were 43 men and 2 women with a median age of 40 years. Most patients had high-grade B-cell lymphoma; 85% had extranodal sites. Prognosis was poor: overall median survival was only 3.8 months. Twelve patients were treated with 3 or more courses of chemotherapy: their median survival was 8 months. In 7 of 12 patients a complete remission was obtained; their median survival was 18 months. A history of AIDS was a poor prognostic factor",

author = "Kersten, {M. J.} and Mertens, {M. J.} and Pals, {S. T.} and P. Reiss and {van Oers}, {M. H.}",

year = "1993",

language = "Dutch",

volume = "137",

pages = "1396--1400",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "Vereniging Nederlands Tijdschrift voor Geneeskunde",

number = "28",

}

TY - JOUR

T1 - Met HIV samenhangend non-Hodgkin-lymfoom bij 45 patiënten; een retrospectieve analyse

AU - Kersten, M. J.

AU - Mertens, M. J.

AU - Pals, S. T.

AU - Reiss, P.

AU - van Oers, M. H.

PY - 1993

Y1 - 1993

N2 - Non-Hodgkin lymphoma is seen in approximately 5% of patients with AIDS. In recent years, the incidence has increased due to an extension of the average lifespan of HIV-infected individuals. In this article we describe the histological and clinical features of 45 patients with HIV-related non-Hodgkin lymphoma seen at the Academic Medical Centre between 1984 and 1991. There were 43 men and 2 women with a median age of 40 years. Most patients had high-grade B-cell lymphoma; 85% had extranodal sites. Prognosis was poor: overall median survival was only 3.8 months. Twelve patients were treated with 3 or more courses of chemotherapy: their median survival was 8 months. In 7 of 12 patients a complete remission was obtained; their median survival was 18 months. A history of AIDS was a poor prognostic factor

AB - Non-Hodgkin lymphoma is seen in approximately 5% of patients with AIDS. In recent years, the incidence has increased due to an extension of the average lifespan of HIV-infected individuals. In this article we describe the histological and clinical features of 45 patients with HIV-related non-Hodgkin lymphoma seen at the Academic Medical Centre between 1984 and 1991. There were 43 men and 2 women with a median age of 40 years. Most patients had high-grade B-cell lymphoma; 85% had extranodal sites. Prognosis was poor: overall median survival was only 3.8 months. Twelve patients were treated with 3 or more courses of chemotherapy: their median survival was 8 months. In 7 of 12 patients a complete remission was obtained; their median survival was 18 months. A history of AIDS was a poor prognostic factor

M3 - Article

C2 - 8345893

SN - 0028-2162

VL - 137

SP - 1396

EP - 1400

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 28

ER -