Projects per year
Personal profile
Research interests
Marie José Kersten is a professor of hematology at Amsterdam University Medical Centers. B cell malignancies are the main focus of research in this department, which together with the departments of Pathology and Experimental Immunology forms the basis for the LYMMCARE Institute (Lymphoma and Myeloma Center Amsterdam). Marie José Kersten is involved in several research projects and she is the principal investigator for several phase I/II clinical trials focusing on the biology and treatment of NHL, Waldenstrom’s macroglobulinemia and Hodgkin lymphoma. She is the chair of the EHA (European Hematology Association) Scientific Working Group Lymphoma. She is the former co-chair of the HOVON (Hemato-Oncologie Volwassenen Nederland) Lymphoma Working Party, and a co-founder and chair of the Board of the HOVON/Lunenburg Lymphoma Phase I/II Consortium (HOVON/LLPC). The main focus of the LLPC is to perform early clinical trials (from first-in-human trials to early phase II trials) in patients with lymphoma. Additionally, she is the co-chair of the Immune Effector Cell Working Party of HOVON. She is also an active member of the international Lunenburg Lymphoma Biomarker Consortium (LLBC) and the European Waldenstrom’s Macroglobulinemia Consortium (EWMC). Another research theme within LYMMCARE is to better understand the biology underlying tumor growth, progression and treatment resistance (in lymphoma, Waldenstrom's macroglobulinemia and multiple myeloma). This research is done in collaboration with the pathology department at the AMC (Pals/Spaargaren).
specialisation
Biology and treatment of lymphoma, with an emphasis on early clinical trials with CAR T-cells
Collaborations and top research areas from the last five years
Projects
- 2 Active
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Kersten M.J.: [NO DATA]
Lantermans, H., van Lier, Y., Minderman, M., Nijland, M., Persoon, S., Vos, J. M., Kersten, M. J. & Stevens, W. S.
16/03/2014 → …
Project: Research
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van Oers M.H.J.: Pathogenesis and Immunotherapy of B cell malignancies
Gerritsen, M., Gillissen, M., Kroeze, A., Schimmel, M., Sins, J., van Tuijn, C., Biemond, B. J., Kater, A. P., Kersten, M. J., Zeerleder, S., Hazenberg, M., Slinger, E. & Tonino, S.
1/01/2006 → …
Project: Research
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Precision medicine in diffuse large B-cell lymphoma: hitting the target
Vermaat, J. S., Pals, S. T., Younes, A., Dreyling, M., Federico, M., Aurer, I., Radford, J. & Kersten, M. J., 2015, In: Haematologica. 100, 8, p. 989-993Research output: Contribution to journal › Editorial › Academic › peer-review
23 Citations (Scopus) -
Diffuse large B cell lymphomas relapsing in the CNS lack oncogenic MYD88 and CD79B mutations
Kersten, M. J., Kraan, W., Doorduijn, J., Bromberg, J., Lam, K., Kluin, P. M., van der Holt, B. J., Spaargaren, M. & Pals, S. T., 2014, In: Blood Cancer Journal. 4, p. e266Research output: Contribution to journal › Comment/Letter to the editor › Academic
8 Citations (Scopus) -
Early discharge after high dose chemotherapy is safe and feasible: a prospective evaluation of 6 years of home care
Mank, A. P. M., Schoonenberg, C., Bleeker, K., Heijmenberg, S., Heer, K. D., van Oers, M. H. J. & Kersten, M. J., 2015, In: Leukemia & lymphoma. 56, 7, p. 2098-2104Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
Long-term follow-up of autologous hematopoietic stem cell transplantation for severe refractory Crohn's disease
Hommes, D. W., Duijvestein, M., Zelinkova, Z., Stokkers, P. C. F., Ley, M. H., Stoker, J., Voermans, C., van Oers, M. H. J. & Kersten, M. J., 2011, In: Journal of Crohn s & colitis. 5, 6, p. 543-549Research output: Contribution to journal › Article › Academic › peer-review
52 Citations (Scopus) -
The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells
Thijssen, R., ter Burg, J., van Bochove, G. G. W., de Rooij, M. F. M., Kuil, A., Jansen, M. H., Kuijpers, T. W., Baars, J. W., Virone-Oddos, A., Spaargaren, M., Egile, C., van Oers, M. H. J., Eldering, E., Kersten, M. J. & Kater, A. P., 2016, In: Leukemia. 30, 2, p. 337-345Research output: Contribution to journal › Article › Academic › peer-review
17 Citations (Scopus)