TY - JOUR
T1 - Mini-report: Microcirculatory flow abnormalities in a patient with severe hyperviscosity syndrome
AU - Ruiz, Carolina
AU - Hernandez, Glenn
AU - Andresen, Max
AU - Ince, Can
AU - Bruhn, Alejandro
PY - 2013
Y1 - 2013
N2 - A 60-year women was admitted to ICU because seizures, poor peripheral perfusion and acute renal failure. In laboratory tests an hyperproteinemia was detected, and therefore an electrophoresis and a bone marrow biopsy were performed, confirming a Waldenström Macroglobulinemia with severe hyperviscosity. Sublingual microcirculation was assessed with videomicroscopy, finding sluggish and intermittent microvascular flow, despite normal lactate and mixed venous O2 saturation. Promptly plasmapheresis was started, with viscosity decrease in parallel with improvement in microvascular flow and clinical status. Three days after the first plasmapheresis the patient was discharged from ICU. This case shows the critical role of viscosity on microcirculatory flow
AB - A 60-year women was admitted to ICU because seizures, poor peripheral perfusion and acute renal failure. In laboratory tests an hyperproteinemia was detected, and therefore an electrophoresis and a bone marrow biopsy were performed, confirming a Waldenström Macroglobulinemia with severe hyperviscosity. Sublingual microcirculation was assessed with videomicroscopy, finding sluggish and intermittent microvascular flow, despite normal lactate and mixed venous O2 saturation. Promptly plasmapheresis was started, with viscosity decrease in parallel with improvement in microvascular flow and clinical status. Three days after the first plasmapheresis the patient was discharged from ICU. This case shows the critical role of viscosity on microcirculatory flow
U2 - https://doi.org/10.3233/CH-2012-1562
DO - https://doi.org/10.3233/CH-2012-1562
M3 - Article
C2 - 22710808
SN - 1386-0291
VL - 54
SP - 33
EP - 38
JO - Clinical Hemorheology and Microcirculation
JF - Clinical Hemorheology and Microcirculation
IS - 1
ER -