[Molecular epidemiology of HIV-1 strains in the Moscow Region]

A. V. Giliazova; P. V. Zenin; A. Iu Pronin; I. L. Serkov; K. M. Khametova; E. A. Orlova-Morozova; E. V. Zhukova; G. V. Kornilaeva; A. O. Pasternak; V. V. Lukashov; E. V. Karamov

[Molecular epidemiology of HIV-1 strains in the Moscow Region]

A. V. Giliazova, P. V. Zenin, A. Iu Pronin, I. L. Serkov, K. M. Khametova, E. A. Orlova-Morozova, E. V. Zhukova, G. V. Kornilaeva, A. O. Pasternak, V. V. Lukashov, E. V. Karamov

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Abstract

The Moscow Region is one of the HIV-1-affected subjects of the Russian Federation; there were 34613 HIV-1-infected subjects as of October 31, 2009. To characterize the molecular epidemiology of HIV-1 in the Moscow Region, the investigators obtained and studied HIV-1 variants from 61 infected subjects of the region, who were major risk groups: intravenous drug users (IDUs) and hetero- and homosexually infected persons. Genetic analysis of HIV-1 variants was carried out by sequencing the gag genes (729 nucleotides in length, including full-length protein p17 and partial p24) andlor env (270 nucleotides in length, V3 region) with further phylogenetic analysis. The findings demonstrated that HIV-1 subtype A variants are dominant in the Moscow Region and detectable in 93.5% of IDUs and 100% of heterosexually infected persons. Phylogenetically (and accordingly epidemiologically) unrelated HIV-1 subtype B strains were revealed in 4 patients, including 2 IDUs

Original language	English
Pages (from-to)	25-29
Journal	Voprosy virusologii
Volume	55
Issue number	5
Publication status	Published - 2010

Cite this

@article{5fb85adb9e1849debbbb57fe427a43b7,

title = "[Molecular epidemiology of HIV-1 strains in the Moscow Region]",

abstract = "The Moscow Region is one of the HIV-1-affected subjects of the Russian Federation; there were 34613 HIV-1-infected subjects as of October 31, 2009. To characterize the molecular epidemiology of HIV-1 in the Moscow Region, the investigators obtained and studied HIV-1 variants from 61 infected subjects of the region, who were major risk groups: intravenous drug users (IDUs) and hetero- and homosexually infected persons. Genetic analysis of HIV-1 variants was carried out by sequencing the gag genes (729 nucleotides in length, including full-length protein p17 and partial p24) andlor env (270 nucleotides in length, V3 region) with further phylogenetic analysis. The findings demonstrated that HIV-1 subtype A variants are dominant in the Moscow Region and detectable in 93.5% of IDUs and 100% of heterosexually infected persons. Phylogenetically (and accordingly epidemiologically) unrelated HIV-1 subtype B strains were revealed in 4 patients, including 2 IDUs",

author = "Giliazova, {A. V.} and Zenin, {P. V.} and Pronin, {A. Iu} and Serkov, {I. L.} and Khametova, {K. M.} and Orlova-Morozova, {E. A.} and Zhukova, {E. V.} and Kornilaeva, {G. V.} and Pasternak, {A. O.} and Lukashov, {V. V.} and Karamov, {E. V.}",

year = "2010",

language = "English",

volume = "55",

pages = "25--29",

journal = "Voprosy virusologii",

issn = "0507-4088",

publisher = "Izdatelstvo Meditsina",

number = "5",

}

TY - JOUR

T1 - [Molecular epidemiology of HIV-1 strains in the Moscow Region]

AU - Giliazova, A. V.

AU - Zenin, P. V.

AU - Pronin, A. Iu

AU - Serkov, I. L.

AU - Khametova, K. M.

AU - Orlova-Morozova, E. A.

AU - Zhukova, E. V.

AU - Kornilaeva, G. V.

AU - Pasternak, A. O.

AU - Lukashov, V. V.

AU - Karamov, E. V.

PY - 2010

Y1 - 2010

N2 - The Moscow Region is one of the HIV-1-affected subjects of the Russian Federation; there were 34613 HIV-1-infected subjects as of October 31, 2009. To characterize the molecular epidemiology of HIV-1 in the Moscow Region, the investigators obtained and studied HIV-1 variants from 61 infected subjects of the region, who were major risk groups: intravenous drug users (IDUs) and hetero- and homosexually infected persons. Genetic analysis of HIV-1 variants was carried out by sequencing the gag genes (729 nucleotides in length, including full-length protein p17 and partial p24) andlor env (270 nucleotides in length, V3 region) with further phylogenetic analysis. The findings demonstrated that HIV-1 subtype A variants are dominant in the Moscow Region and detectable in 93.5% of IDUs and 100% of heterosexually infected persons. Phylogenetically (and accordingly epidemiologically) unrelated HIV-1 subtype B strains were revealed in 4 patients, including 2 IDUs

AB - The Moscow Region is one of the HIV-1-affected subjects of the Russian Federation; there were 34613 HIV-1-infected subjects as of October 31, 2009. To characterize the molecular epidemiology of HIV-1 in the Moscow Region, the investigators obtained and studied HIV-1 variants from 61 infected subjects of the region, who were major risk groups: intravenous drug users (IDUs) and hetero- and homosexually infected persons. Genetic analysis of HIV-1 variants was carried out by sequencing the gag genes (729 nucleotides in length, including full-length protein p17 and partial p24) andlor env (270 nucleotides in length, V3 region) with further phylogenetic analysis. The findings demonstrated that HIV-1 subtype A variants are dominant in the Moscow Region and detectable in 93.5% of IDUs and 100% of heterosexually infected persons. Phylogenetically (and accordingly epidemiologically) unrelated HIV-1 subtype B strains were revealed in 4 patients, including 2 IDUs

M3 - Article

C2 - 21260992

SN - 0507-4088

VL - 55

SP - 25

EP - 29

JO - Voprosy virusologii

JF - Voprosy virusologii

IS - 5

ER -