Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237)

Jeroen A. C. M. Goos; Joost Verbeek; Albert A. Geldof; Mark A. van de Wiel; Kevin A. Adamzek; Pien M. Delis-Van Diemen; Stephen G. Stroud; Daniel P. Bradley; Gerrit A. Meijer; Otto S. Hoekstra; Remond J. A. Fijneman; Albert D. Windhorst; AC Hiemstra

doi:https://doi.org/10.1016/j.nucmedbio.2015.08.007

Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237)

Jeroen A. C. M. Goos, Joost Verbeek, Albert A. Geldof, Mark A. van de Wiel, Kevin A. Adamzek, Pien M. Delis-Van Diemen, Stephen G. Stroud, Daniel P. Bradley, Gerrit A. Meijer, Otto S. Hoekstra, Remond J. A. Fijneman, Albert D. Windhorst, AC Hiemstra

Research output: Contribution to journal › Article › Academic › peer-review

9 Citations (Scopus)

Original language	English
Pages (from-to)	63-72
Journal	Nuclear medicine and biology
Volume	43
Issue number	1
DOIs	https://doi.org/10.1016/j.nucmedbio.2015.08.007
Publication status	Published - Jan 2016

Keywords

AURKA
Alisertib
Carbon-11
PET
Tritium

Access to Document

https://doi.org/10.1016/j.nucmedbio.2015.08.007

Cite this

Goos, J. A. C. M., Verbeek, J., Geldof, A. A., van de Wiel, M. A., Adamzek, K. A., Delis-Van Diemen, P. M., Stroud, S. G., Bradley, D. P., Meijer, G. A., Hoekstra, O. S., Fijneman, R. J. A., Windhorst, A. D., & Hiemstra, AC. (2016). Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237). Nuclear medicine and biology, 43(1), 63-72. https://doi.org/10.1016/j.nucmedbio.2015.08.007

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title = "Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237)",

keywords = "AURKA, Alisertib, Carbon-11, PET, Tritium",

author = "Goos, {Jeroen A. C. M.} and Joost Verbeek and Geldof, {Albert A.} and {van de Wiel}, {Mark A.} and Adamzek, {Kevin A.} and {Delis-Van Diemen}, {Pien M.} and Stroud, {Stephen G.} and Bradley, {Daniel P.} and Meijer, {Gerrit A.} and Hoekstra, {Otto S.} and Fijneman, {Remond J. A.} and Windhorst, {Albert D.} and AC Hiemstra",

year = "2016",

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doi = "https://doi.org/10.1016/j.nucmedbio.2015.08.007",

language = "English",

volume = "43",

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journal = "Nuclear medicine and biology",

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Goos, JACM, Verbeek, J, Geldof, AA, van de Wiel, MA, Adamzek, KA, Delis-Van Diemen, PM, Stroud, SG, Bradley, DP, Meijer, GA, Hoekstra, OS, Fijneman, RJA, Windhorst, AD & Hiemstra, AC 2016, 'Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237)', Nuclear medicine and biology, vol. 43, no. 1, pp. 63-72. https://doi.org/10.1016/j.nucmedbio.2015.08.007

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AU - Goos, Jeroen A. C. M.

AU - Verbeek, Joost

AU - Geldof, Albert A.

AU - van de Wiel, Mark A.

AU - Adamzek, Kevin A.

AU - Delis-Van Diemen, Pien M.

AU - Stroud, Stephen G.

AU - Bradley, Daniel P.

AU - Meijer, Gerrit A.

AU - Hoekstra, Otto S.

AU - Fijneman, Remond J. A.

AU - Windhorst, Albert D.

AU - Hiemstra, AC

PY - 2016/1

Y1 - 2016/1

KW - AURKA

KW - Alisertib

KW - Carbon-11

KW - PET

KW - Tritium

U2 - https://doi.org/10.1016/j.nucmedbio.2015.08.007

DO - https://doi.org/10.1016/j.nucmedbio.2015.08.007

M3 - Article

C2 - 26432753

SN - 0969-8051

VL - 43

SP - 63

EP - 72

JO - Nuclear medicine and biology

JF - Nuclear medicine and biology

IS - 1

ER -