Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications

Ryosuke Shirasaki; Ricardo de Matos Simoes; Sara Gandolfi; Geoffrey Matthews; Dennis Buckley; Joseline Raja; Quinlan Sievers; Johanna Bruggenthies; Olga Dashevsky; Haley Poarch; Huihui Tang; Megan Bariteau; Michal Sheffer; Yiguo Hu; Sondra Downey-Kopyscinski; Paul Hengeveld; Brian J. Glassner; Eugen Dhimolea; Christopher Ott; Tinghu Zhang; Nicholas Kwiatkowski; Jacob Laubach; Robert Schlossman; Aedin Culhane; Paul G. Richardson; Richard Groen; Eric Fischer; Francisca Vazquez; Aviad Tsherniak; William Hahn; Joan Levy; Daniel Auclair; Jonathan Licht; Jonathan Keats; Lawrence Boise; Benjamin Ebert; James Bradner; Nathanael Gray; Constantine Mitsiades

Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications

Ryosuke Shirasaki, Ricardo de Matos Simoes, Sara Gandolfi, Geoffrey Matthews, Dennis Buckley, Joseline Raja, Quinlan Sievers, Johanna Bruggenthies, Olga Dashevsky, Haley Poarch, Huihui Tang, Megan Bariteau, Michal Sheffer, Yiguo Hu, Sondra Downey-Kopyscinski, Paul Hengeveld, Brian J. Glassner, Eugen Dhimolea, Christopher Ott, Tinghu ZhangNicholas Kwiatkowski, Jacob Laubach, Robert Schlossman, Aedin Culhane, Paul G. Richardson, Richard Groen, Eric Fischer, Francisca Vazquez, Aviad Tsherniak, William Hahn, Joan Levy, Daniel Auclair, Jonathan Licht, Jonathan Keats, Lawrence Boise, Benjamin Ebert, James Bradner, Nathanael Gray, Constantine Mitsiades

Research output: Contribution to journal › Meeting Abstract › Academic

Original language	English
Pages (from-to)	E134-E134
Journal	Clinical Lymphoma Myeloma and Leukemia
Volume	19
Issue number	10
Publication status	Published - Oct 2019

Keywords

E3 ligase
High-risk cytogenetics
PROTACs

Cite this

Shirasaki, R., Simoes, R. D. M., Gandolfi, S., Matthews, G., Buckley, D., Raja, J., Sievers, Q., Bruggenthies, J., Dashevsky, O., Poarch, H., Tang, H., Bariteau, M., Sheffer, M., Hu, Y., Downey-Kopyscinski, S., Hengeveld, P., Glassner, B. J., Dhimolea, E., Ott, C., ... Mitsiades, C. (2019). Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications. Clinical Lymphoma Myeloma and Leukemia, 19(10), E134-E134.

@article{e3db045bf1e84fa4ae6487abc6f3430b,

title = "Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications",

keywords = "E3 ligase, High-risk cytogenetics, PROTACs",

author = "Ryosuke Shirasaki and Simoes, {Ricardo de Matos} and Sara Gandolfi and Geoffrey Matthews and Dennis Buckley and Joseline Raja and Quinlan Sievers and Johanna Bruggenthies and Olga Dashevsky and Haley Poarch and Huihui Tang and Megan Bariteau and Michal Sheffer and Yiguo Hu and Sondra Downey-Kopyscinski and Paul Hengeveld and Glassner, {Brian J.} and Eugen Dhimolea and Christopher Ott and Tinghu Zhang and Nicholas Kwiatkowski and Jacob Laubach and Robert Schlossman and Aedin Culhane and Richardson, {Paul G.} and Richard Groen and Eric Fischer and Francisca Vazquez and Aviad Tsherniak and William Hahn and Joan Levy and Daniel Auclair and Jonathan Licht and Jonathan Keats and Lawrence Boise and Benjamin Ebert and James Bradner and Nathanael Gray and Constantine Mitsiades",

year = "2019",

month = oct,

language = "English",

volume = "19",

pages = "E134--E134",

journal = "Clinical Lymphoma Myeloma and Leukemia",

issn = "2152-2650",

publisher = "Cancer Media Group",

number = "10",

}

Shirasaki, R, Simoes, RDM, Gandolfi, S, Matthews, G, Buckley, D, Raja, J, Sievers, Q, Bruggenthies, J, Dashevsky, O, Poarch, H, Tang, H, Bariteau, M, Sheffer, M, Hu, Y, Downey-Kopyscinski, S, Hengeveld, P, Glassner, BJ, Dhimolea, E, Ott, C, Zhang, T, Kwiatkowski, N, Laubach, J, Schlossman, R, Culhane, A, Richardson, PG, Groen, R, Fischer, E, Vazquez, F, Tsherniak, A, Hahn, W, Levy, J, Auclair, D, Licht, J, Keats, J, Boise, L, Ebert, B, Bradner, J, Gray, N & Mitsiades, C 2019, 'Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications', Clinical Lymphoma Myeloma and Leukemia, vol. 19, no. 10, pp. E134-E134.

TY - JOUR

T1 - Molecular markers of myeloma cell sensitivity vs. resistance to heterobifunctional degraders of oncoproteins: therapeutic implications

AU - Shirasaki, Ryosuke

AU - Simoes, Ricardo de Matos

AU - Gandolfi, Sara

AU - Matthews, Geoffrey

AU - Buckley, Dennis

AU - Raja, Joseline

AU - Sievers, Quinlan

AU - Bruggenthies, Johanna

AU - Dashevsky, Olga

AU - Poarch, Haley

AU - Tang, Huihui

AU - Bariteau, Megan

AU - Sheffer, Michal

AU - Hu, Yiguo

AU - Downey-Kopyscinski, Sondra

AU - Hengeveld, Paul

AU - Glassner, Brian J.

AU - Dhimolea, Eugen

AU - Ott, Christopher

AU - Zhang, Tinghu

AU - Kwiatkowski, Nicholas

AU - Laubach, Jacob

AU - Schlossman, Robert

AU - Culhane, Aedin

AU - Richardson, Paul G.

AU - Groen, Richard

AU - Fischer, Eric

AU - Vazquez, Francisca

AU - Tsherniak, Aviad

AU - Hahn, William

AU - Levy, Joan

AU - Auclair, Daniel

AU - Licht, Jonathan

AU - Keats, Jonathan

AU - Boise, Lawrence

AU - Ebert, Benjamin

AU - Bradner, James

AU - Gray, Nathanael

AU - Mitsiades, Constantine

PY - 2019/10

Y1 - 2019/10

KW - E3 ligase

KW - High-risk cytogenetics

KW - PROTACs

M3 - Meeting Abstract

SN - 2152-2650

VL - 19

SP - E134-E134

JO - Clinical Lymphoma Myeloma and Leukemia

JF - Clinical Lymphoma Myeloma and Leukemia

IS - 10

ER -