Multisystem inflammatory syndrome in children (MIS-C) in the paediatric intensive care unit

Currently the world is facing a pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although most children and adolescents are asymptomatic or only have mild symptoms during the acute stage of infection, a severe post-infectious syndrome may occur several weeks after a SARS-CoV-2 infection, known as multisystem inflammatory syndrome in children (MIS-C). The clinical symptoms of MIS-C mimic Kawasaki disease, with fever, a maculopapular rash, conjunctivitis, peripheral oedema and palmar erythema. However, different to Kawasaki disease, many MIS-C patients primarily present with gastrointestinal symptoms or cardiovascular involvement requiring vasopressor or inotropic support.