Neuronal Regulation of Mucosal Immune Responses

Wouter J. de Jonge

doi:https://doi.org/10.1016/B978-0-12-415847-4.00046-X

Neuronal Regulation of Mucosal Immune Responses

Wouter J. de Jonge

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

2 Citations (Scopus)

Abstract

In this chapter, the current understanding of how innate mucosal immunity can be influenced by the neuronal system will be highlighted, and the cell types and receptors documented to play a role in this interaction discussed. We will focus on the direct neuronal regulatory mechanisms, notwithstanding current advances regarding the role of gut microbes, including gastrointestinal commensals and pathogens, in modulating communication in the gut-brain axis. These aspects of gut-brain communication will be discussed elsewhere.

Original language	English
Title of host publication	Mucosal Immunology
Subtitle of host publication	Fourth Edition
Publisher	Elsevier Inc.
Pages	929-942
Number of pages	14
Volume	1-2
ISBN (Electronic)	9780124159754
ISBN (Print)	9780124158474
DOIs	https://doi.org/10.1016/B978-0-12-415847-4.00046-X
Publication status	Published - 1 Apr 2015

Keywords

Cholinergic anti-inflammatory reflex
Innate mucosal immunity
Intestinal immune responses
Mucosal immune responses
Neural reflexes
Neuronal regulation
Parasympathetic (vagal) neurotransmitters
Sympathetic neurotransmitters

Access to Document

https://doi.org/10.1016/B978-0-12-415847-4.00046-X

Cite this

@inbook{68fac43cdc544140959a84ff90cd7598,

title = "Neuronal Regulation of Mucosal Immune Responses",

abstract = "In this chapter, the current understanding of how innate mucosal immunity can be influenced by the neuronal system will be highlighted, and the cell types and receptors documented to play a role in this interaction discussed. We will focus on the direct neuronal regulatory mechanisms, notwithstanding current advances regarding the role of gut microbes, including gastrointestinal commensals and pathogens, in modulating communication in the gut-brain axis. These aspects of gut-brain communication will be discussed elsewhere.",

keywords = "Cholinergic anti-inflammatory reflex, Innate mucosal immunity, Intestinal immune responses, Mucosal immune responses, Neural reflexes, Neuronal regulation, Parasympathetic (vagal) neurotransmitters, Sympathetic neurotransmitters",

author = "{de Jonge}, {Wouter J.}",

note = "Funding Information: The author thankfully acknowledges grant support from Top Institute Pharma and Glaxo-SmithKline, program grant T1-215. Further support was received by a grant from the Netherlands Foundation for Scientific Research (NWO-VIDI). Publisher Copyright: {\textcopyright} 2015 Elsevier Inc. All rights reserved.",

year = "2015",

month = apr,

day = "1",

doi = "https://doi.org/10.1016/B978-0-12-415847-4.00046-X",

language = "English",

isbn = "9780124158474",

volume = "1-2",

pages = "929--942",

booktitle = "Mucosal Immunology",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Neuronal Regulation of Mucosal Immune Responses

AU - de Jonge, Wouter J.

N1 - Funding Information: The author thankfully acknowledges grant support from Top Institute Pharma and Glaxo-SmithKline, program grant T1-215. Further support was received by a grant from the Netherlands Foundation for Scientific Research (NWO-VIDI). Publisher Copyright: © 2015 Elsevier Inc. All rights reserved.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - In this chapter, the current understanding of how innate mucosal immunity can be influenced by the neuronal system will be highlighted, and the cell types and receptors documented to play a role in this interaction discussed. We will focus on the direct neuronal regulatory mechanisms, notwithstanding current advances regarding the role of gut microbes, including gastrointestinal commensals and pathogens, in modulating communication in the gut-brain axis. These aspects of gut-brain communication will be discussed elsewhere.

AB - In this chapter, the current understanding of how innate mucosal immunity can be influenced by the neuronal system will be highlighted, and the cell types and receptors documented to play a role in this interaction discussed. We will focus on the direct neuronal regulatory mechanisms, notwithstanding current advances regarding the role of gut microbes, including gastrointestinal commensals and pathogens, in modulating communication in the gut-brain axis. These aspects of gut-brain communication will be discussed elsewhere.

KW - Cholinergic anti-inflammatory reflex

KW - Innate mucosal immunity

KW - Intestinal immune responses

KW - Mucosal immune responses

KW - Neural reflexes

KW - Neuronal regulation

KW - Parasympathetic (vagal) neurotransmitters

KW - Sympathetic neurotransmitters

UR - http://www.scopus.com/inward/record.url?scp=84939484585&partnerID=8YFLogxK

U2 - https://doi.org/10.1016/B978-0-12-415847-4.00046-X

DO - https://doi.org/10.1016/B978-0-12-415847-4.00046-X

M3 - Chapter

SN - 9780124158474

VL - 1-2

SP - 929

EP - 942

BT - Mucosal Immunology

PB - Elsevier Inc.

ER -

Neuronal Regulation of Mucosal Immune Responses

Abstract

Keywords

Access to Document

Other files and links

Cite this