Non-invasive imaging of activation times during drug inducedconduction changes

A. C. Linnenbank, A. van Oosterom, T. Oostendorp, P. F.H.M. van Dessel, A. C. van Rossum, R. Coronel, H. L. Tan, J. M.T. de Bakker

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The feasibility was studied of monitoring changes in the activation sequence of the heart on the basis of potentials observed on the body surface potentials during a clinical procedure involving the infusion of a sodium channel blocker. The changes in the activation pattern were derived from an inverse procedure (activation time imaging). The results suggest that this is indeed possible, in spite of the fact that the number of ECGs used in the inverse procedure was 65. The quality of the results was attributed to recent improvements in the algorithm performing the imaging procedure.

Original languageEnglish
Title of host publicationIFMBE Proceedings
EditorsSun I. Kim, Tae Suk Suh
PublisherSpringer Verlag
Number of pages4
ISBN (Print)9783540368397
Publication statusPublished - 2007
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: 27 Aug 20061 Sep 2006

Publication series

NameIFMBE Proceedings


Conference10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/TerritoryKorea, Republic of


  • Activation time imaging
  • Body surface mapping
  • Inverse procedure
  • Sodium channel blocker

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