Normal IncA expression and fusogenicity of inclusions in Chlamydia trachomatis isolates with the incA I47T mutation

Y. Pannekoek; A. van der Ende; P. P. Eijk; J. van Marle; M. A. de Witte; J. M. Ossewaarde; A. J. van den Brule; S. A. Morré; J. Dankert

doi:https://doi.org/10.1128/IAI.69.7.4654-4656.2001

Normal IncA expression and fusogenicity of inclusions in Chlamydia trachomatis isolates with the incA I47T mutation

Y. Pannekoek, A. van der Ende, P. P. Eijk, J. van Marle, M. A. de Witte, J. M. Ossewaarde, A. J. van den Brule, S. A. Morré, J. Dankert

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12 Citations (Scopus)

Abstract

To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the membrane of one large single inclusion. In conclusion, the incA I47T mutation is not associated with the nonfusogenic phenotype

Original language	English
Pages (from-to)	4654-4656
Journal	Infection and immunity
Volume	69
Issue number	7
DOIs	https://doi.org/10.1128/IAI.69.7.4654-4656.2001
Publication status	Published - 2001

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https://doi.org/10.1128/IAI.69.7.4654-4656.2001

Cite this

@article{4ab4a6106c724c40a6d8a8cf943167b6,

title = "Normal IncA expression and fusogenicity of inclusions in Chlamydia trachomatis isolates with the incA I47T mutation",

abstract = "To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the membrane of one large single inclusion. In conclusion, the incA I47T mutation is not associated with the nonfusogenic phenotype",

author = "Y. Pannekoek and {van der Ende}, A. and Eijk, {P. P.} and {van Marle}, J. and {de Witte}, {M. A.} and Ossewaarde, {J. M.} and {van den Brule}, {A. J.} and Morr{\'e}, {S. A.} and J. Dankert",

year = "2001",

doi = "https://doi.org/10.1128/IAI.69.7.4654-4656.2001",

language = "English",

volume = "69",

pages = "4654--4656",

journal = "Infection and immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Normal IncA expression and fusogenicity of inclusions in Chlamydia trachomatis isolates with the incA I47T mutation

AU - Pannekoek, Y.

AU - van der Ende, A.

AU - Eijk, P. P.

AU - van Marle, J.

AU - de Witte, M. A.

AU - Ossewaarde, J. M.

AU - van den Brule, A. J.

AU - Morré, S. A.

AU - Dankert, J.

PY - 2001

Y1 - 2001

N2 - To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the membrane of one large single inclusion. In conclusion, the incA I47T mutation is not associated with the nonfusogenic phenotype

AB - To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were identified. Seven isolates (28%) had the I47T mutation. Isolates representing the four sequence types expressed IncA in the membrane of one large single inclusion. In conclusion, the incA I47T mutation is not associated with the nonfusogenic phenotype

U2 - https://doi.org/10.1128/IAI.69.7.4654-4656.2001

DO - https://doi.org/10.1128/IAI.69.7.4654-4656.2001

M3 - Article

C2 - 11402010

SN - 0019-9567

VL - 69

SP - 4654

EP - 4656

JO - Infection and immunity

JF - Infection and immunity

IS - 7

ER -