Projects per year
Personal profile
Research interests
We study the molecular epidemiology and population structure of the main pathogens causing meningitis, Neisseria meningitidis and Streptococcus pneumoniae, and of Chlamydia species causing respiratory infections and sexual transmitted disease. In addition, we study the pathogenesis of meningococcal and invasive pneumococcal disease. We are particularly interested in the bacterial stress response and its regulation by small RNAs (ribo-regulation) in conjunction with alternative sigma factors like sigmaE.
In collaborative studies with Dr. D. van de Beek (Department of Neurology, AMC) we investigate clinical aspects of bacterial meningitis as well correlation between clinical features, outcome and host and bacterial factors.
specialisation
Collaborations and top research areas from the last five years
Projects
- 1 Active
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van der Ende A.: Bacterial meningitis
van der Ende, A., Pannekoek, Y., Bovenkerk, S., Feller, M., Bril - Keijzers, W., Schipper, K., de Beer - Schuurman, I., Huis in 't Veld, R. & Jim, K.
1/01/2006 → …
Project: Research
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The streptococcal phase-variable type I restriction modification system SsuCC20p dictates the methylome of Streptococcus suis impacting the transcriptome and virulence in a zebrafish larvae infection model
Roodsant, T. J., van der Putten, B., Brizuela, J., Coolen, J. P. M., Baltussen, T. J. H., Schipper, K., Pannekoek, Y., van der Ark, K. C. H. & Schultsz, C., 16 Jan 2024, In: MBio. 15, 1, p. e0225923Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Neisseria meningitidis Sibling Small Regulatory RNAs Connect Metabolism with Colonization by Controlling Propionate Use
Man-Bovenkerk, S., Schipper, K., van Sorge, N. M., Speijer, D., van der Ende, A. & Pannekoek, Y., 21 Mar 2023, In: Journal of Bacteriology. 205, 3, p. e0046222 e00462-22.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Use of gene sequences as type for naming prokaryotes: Recommendations of the international committee on the taxonomy of chlamydiae
Greub, G., Pillonel, T., Bavoil, P. M., Borel, N., Campbell, L. A., Dean, D., Hefty, S., Horn, M., Morré, S. A., Ouellette, S. P., Pannekoek, Y., Puolakkainen, M., Timms, P., Valdivia, R. & Vanrompay, D., 1 Sept 2023, In: New Microbes and New Infections. 54, 101158.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Whole-genome sequencing of Chlamydia psittaci from Australasian avian hosts: A genomics approach to a pathogen that still ruffles feathers
Kasimov, V., White, R. T., Foxwell, J., Jenkins, C., Gedye, K., Pannekoek, Y. & Jelocnik, M., 2023, In: Microbial genomics. 9, 7, 001072.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Call for consensus in Chlamydia trachomatis nomenclature: moving from biovars, serovars, and serotypes to genovariants and genotypes
the ICSP Subcommittee on the Taxonomy of Chlamydiae, Jun 2022, In: Clinical Microbiology and Infection. 28, 6, p. 761-763 3 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open Access6 Citations (Scopus)
Datasets
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Additional file 2: Table S2. of Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease
Versteeg, B. (Creator), Bruisten, S. M. (Creator), Pannekoek, Y. (Creator), Jolley, K. A. (Creator), Maiden, M. C. J. (Creator), van der Ende, A. (Contributor) & Harrison, O. B. (Creator), Figshare, 2018
DOI: 10.6084/m9.figshare.5876325, https://springernature.figshare.com/articles/Additional_file_2_Table_S2_of_Genomic_analyses_of_the_Chlamydia_trachomatis_core_genome_show_an_association_between_chromosomal_genome_plasmid_type_and_disease/5876325
Dataset
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Additional file 5: Table S4. of Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease
Jolley, K. A. (Creator), Maiden, M. C. J. (Creator), Versteeg, B. (Creator), Bruisten, S. M. (Creator), Pannekoek, Y. (Creator), van der Ende, A. (Contributor) & Harrison, O. B. (Creator), Figshare, 2018
DOI: 10.6084/m9.figshare.5876370, https://springernature.figshare.com/articles/Additional_file_5_Table_S4_of_Genomic_analyses_of_the_Chlamydia_trachomatis_core_genome_show_an_association_between_chromosomal_genome_plasmid_type_and_disease/5876370
Dataset
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Additional file 5: Table S4. of Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease
Versteeg, B. (Creator), Bruisten, S. M. (Creator), Pannekoek, Y. (Creator), Jolley, K. A. (Creator), Maiden, M. C. J. (Creator), van der Ende, A. (Contributor) & Harrison, O. B. (Creator), Figshare, 2018
DOI: 10.6084/m9.figshare.5876370.v1, https://springernature.figshare.com/articles/Additional_file_5_Table_S4_of_Genomic_analyses_of_the_Chlamydia_trachomatis_core_genome_show_an_association_between_chromosomal_genome_plasmid_type_and_disease/5876370/1
Dataset
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Supplementary Material for: Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant Staphylococcus aureus to Human Group IIA-Secreted Phospholipase A2 and Daptomycin
Kuijk, M. M. (Contributor), Wu, Y. (Contributor), Shanlitourk, G. (Contributor), Payré, C. (Contributor), Lambeau, G. (Contributor), Man-Bovenkerk, S. (Contributor), Herrmann, J. (Contributor), Müller, R. (Contributor), Pannekoek, Y. (Contributor) & Touqui, L. (Contributor), Karger Publishers, 2022
DOI: 10.6084/m9.figshare.21679874.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Interference_with_Lipoprotein_Maturation_Sensitizes_Methicillin-Resistant_b_i_Staphylococcus_aureus_i_b_to_Human_Group_IIA-Secreted_Phospholipase_A_sub_2_sub_and_Daptomycin/21679874/1
Dataset
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Supplementary Table S1 from Sequencing of the variable region of rpsB to discriminate between Streptococcus pneumoniae and other streptococcal species.
Wyllie, A. L. (Creator), Pannekoek, Y. (Creator), Bovenkerk, S. (Creator), van Engelsdorp Gastelaars, J. (Contributor), Ferwerda, B. (Creator), van de Beek, D. (Contributor), Sanders, E. A. M. (Creator), Trzciński, K. (Creator), van der Ende, A. (Contributor), Gastelaars, J. V. E. (Creator) & Beek, D. V. D. (Creator), The Royal Society, 2017
DOI: 10.6084/m9.figshare.5345950, https://rs.figshare.com/articles/dataset/Supplementary_Table_S1_from_Sequencing_of_the_variable_region_of_i_rpsB_i_to_discriminate_between_i_Streptococcus_pneumoniae_i_and_other_streptococcal_species/5345950
Dataset