Research output per year
Research output per year
Personal profile
specialisation
Microbial Genomics, Bioinformatics, Molecular biology, Microbiology
Research interests
I study the zoonotic pathogen Streptococcus suis. It is a gram positive bacterium virtually ubiqutuous in the porcine population. Being a streptococcal bacteria, it shows very high genomic diversity. However, only a few genomic profile appear to be capable of causing systemic infections in humans.
My research focuses on using whole genome sequencing data to identify evolutionary events that have led certain S. suis lineages to acquire zoonotic potential. Moreover, I validate potential zoonotic factors in models of humans infections in the lab.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
- 4 Article
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Molecular Epidemiology of Underreported Emerging Zoonotic Pathogen Streptococcus suis in Europe
Brizuela, J., Roodsant, T. J., Hasnoe, Q., van der Putten, B. C. L., Kozakova, J., Slotved, H-C., van der Linden, M., de Beer-Schuurman, I. G. A., Sadowy, E., Sáez-Nieto, J. A., Chalker, V. J., van der Ark, K. C. H. & Schultsz, C., 1 Mar 2024, In: Emerging infectious diseases. 30, 3, p. 413-422 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture
Eilers, K., Hoong Yam, J. K., Liu, X., Goh, Y. F., To, K-N., Paracuellos, P., Morton, R., Brizuela, J., Hui Yong, A. M., Givskov, M., Freibert, S-A., Bange, G., Rice, S. A., Steinchen, W. & Filloux, A., 1 Feb 2024, In: Journal of Biological Chemistry. 300, 2, 105659.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The streptococcal phase-variable type I restriction modification system SsuCC20p dictates the methylome of Streptococcus suis impacting the transcriptome and virulence in a zebrafish larvae infection model
Roodsant, T. J., van der Putten, B., Brizuela, J., Coolen, J. P. M., Baltussen, T. J. H., Schipper, K., Pannekoek, Y., van der Ark, K. C. H. & Schultsz, C., 16 Jan 2024, In: MBio. 15, 1, p. e0225923Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Streptococcus suis outbreak caused by an emerging zoonotic strain with acquired multi-drug resistance in Thailand
Brizuela, J., Kajeekul, R., Roodsant, T. J., Riwload, A., Boueroy, P., Pattanapongpaibool, A., Thaipadungpanit, J., Jenjaroenpun, P., Wongsurawat, T., Batty, E. M., van der Putten, B. C. L., Schultsz, C. & Kerdsin, A., 15 Feb 2023, In: Microbial genomics. 9, 2, 14 p., 000952.Research output: Contribution to journal › Article › Academic › peer-review
Open Access8 Citations (Scopus)