TY - JOUR
T1 - Organ donation and transplantation: a multi-stakeholder call to action
AU - Vanholder, Raymond
AU - Domínguez-Gil, Beatriz
AU - Busic, Mirela
AU - Cortez-Pinto, Helena
AU - Craig, Jonathan C.
AU - Jager, Kitty J.
AU - Mahillo, Beatriz
AU - Stel, Vianda S.
AU - Valentin, Maria O.
AU - Zoccali, Carmine
AU - Oniscu, Gabriel C.
N1 - Funding Information: Despite substantial national and trans-national progress over the past five decades, several fundamental questions in the field of transplantation remain unsolved. These range from the basic patho-physiology, immunology and molecular biology of the transplantation process and the response of the host to the donor organ, to clinical aspects and those relating to organizational, societal, psychological and quality of life issues. Transplantation research deserves specific attention for funding and support. Patients, medical professionals and society as a whole will benefit from research streamlined to focus on a number of areas and topics of prime interest (box 2), with the aim of better shaping future priorities, developments and policy actions in the field. Publisher Copyright: © 2021, Springer Nature Limited. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/8
Y1 - 2021/8
N2 - Although overall donation and transplantation activity is higher in Europe than on other continents, differences between European countries in almost every aspect of transplantation activity (for example, in the number of transplantations, the number of people with a functioning graft, in rates of living versus deceased donation, and in the use of expanded criteria donors) suggest that there is ample room for improvement. Herein we review the policy and clinical measures that should be considered to increase access to transplantation and improve post-transplantation outcomes. This Roadmap, generated by a group of major European stakeholders collaborating within a Thematic Network, presents an outline of the challenges to increasing transplantation rates and proposes 12 key areas along with specific measures that should be considered to promote transplantation. This framework can be adopted by countries and institutions that are interested in advancing transplantation, both within and outside the European Union. Within this framework, a priority ranking of initiatives is suggested that could serve as the basis for a new European Union Action Plan on Organ Donation and Transplantation.
AB - Although overall donation and transplantation activity is higher in Europe than on other continents, differences between European countries in almost every aspect of transplantation activity (for example, in the number of transplantations, the number of people with a functioning graft, in rates of living versus deceased donation, and in the use of expanded criteria donors) suggest that there is ample room for improvement. Herein we review the policy and clinical measures that should be considered to increase access to transplantation and improve post-transplantation outcomes. This Roadmap, generated by a group of major European stakeholders collaborating within a Thematic Network, presents an outline of the challenges to increasing transplantation rates and proposes 12 key areas along with specific measures that should be considered to promote transplantation. This framework can be adopted by countries and institutions that are interested in advancing transplantation, both within and outside the European Union. Within this framework, a priority ranking of initiatives is suggested that could serve as the basis for a new European Union Action Plan on Organ Donation and Transplantation.
UR - http://www.scopus.com/inward/record.url?scp=85105734098&partnerID=8YFLogxK
U2 - https://doi.org/10.1038/s41581-021-00425-3
DO - https://doi.org/10.1038/s41581-021-00425-3
M3 - Review article
C2 - 33953367
SN - 1759-5061
VL - 17
SP - 554
EP - 568
JO - Nature reviews. Nephrology
JF - Nature reviews. Nephrology
IS - 8
ER -