TY - JOUR
T1 - Osteitic bone in recalcitrant chronic rhinosinusitis
AU - Videler, W. J. M.
AU - Georgalas, C.
AU - Menger, D. J.
AU - Freling, N. J. M.
AU - van Drunen, C. M.
AU - Fokkens, W. J.
PY - 2011
Y1 - 2011
N2 - There is increasing interest in the underlying bone of the paranasal sinuses as an important player in recalcitrant Chronic Rhinosinusitis. Close inspection of CT scans often reveals areas of increased bone density and irregular thickening of the sinus walls. This osteitic bone could at least partly explain, why inflammation of the mucosa persists. We searched PubMed for all relevant studies, using the following text words: chronic rhinosinusitis, sinusitis, bone, osteitis, osteomyelitis, histology, and treatment. Cited references of retrieved articles were also examined. Background, available data, potential diagnostic options, treatment implications, and suggestions for future research are discussed. Osteitis is associated with CRS, however its role in the pathogenic process is not well defined. More research is needed
AB - There is increasing interest in the underlying bone of the paranasal sinuses as an important player in recalcitrant Chronic Rhinosinusitis. Close inspection of CT scans often reveals areas of increased bone density and irregular thickening of the sinus walls. This osteitic bone could at least partly explain, why inflammation of the mucosa persists. We searched PubMed for all relevant studies, using the following text words: chronic rhinosinusitis, sinusitis, bone, osteitis, osteomyelitis, histology, and treatment. Cited references of retrieved articles were also examined. Background, available data, potential diagnostic options, treatment implications, and suggestions for future research are discussed. Osteitis is associated with CRS, however its role in the pathogenic process is not well defined. More research is needed
U2 - https://doi.org/10.4193/Rhino10.158
DO - https://doi.org/10.4193/Rhino10.158
M3 - Review article
C2 - 21743867
SN - 0300-0729
VL - 49
SP - 139
EP - 147
JO - Rhinology
JF - Rhinology
IS - 2
ER -