Peripheral and central serotonin in the regulation of glucose metabolism

Mireille J. Serlie

doi:https://doi.org/10.1016/B978-0-444-64125-0.00045-1

Peripheral and central serotonin in the regulation of glucose metabolism

Mireille J. Serlie

Endocrinology (AMC)

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

1 Citation (Scopus)

Abstract

The regulation of glucose metabolism is complex and involves control through hormonal, neuroendocrine, and nutritional factors. Besides the well-known glucoregulatory effects of hormones such as insulin, glucagon, and cortisol, modulation of plasma glucose and insulin also occurs through central and peripheral serotonin signaling. The effects are serotonin receptor-specific, differ between species, and are dependent on the metabolic condition.

Original language	English
Title of host publication	Handbook of Behavioral Neuroscience
Publisher	Elsevier B.V
Pages	893-900
Number of pages	8
Volume	31
DOIs	https://doi.org/10.1016/B978-0-444-64125-0.00045-1
Publication status	Published - 2020

Publication series

Name	Handbook of Behavioral Neuroscience
Volume	31

Keywords

Brain
Diabetes
Glucose
Insulin
Insulin resistance
Serotonin (5-HT)
β-cells

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https://doi.org/10.1016/B978-0-444-64125-0.00045-1

Cite this

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abstract = "The regulation of glucose metabolism is complex and involves control through hormonal, neuroendocrine, and nutritional factors. Besides the well-known glucoregulatory effects of hormones such as insulin, glucagon, and cortisol, modulation of plasma glucose and insulin also occurs through central and peripheral serotonin signaling. The effects are serotonin receptor-specific, differ between species, and are dependent on the metabolic condition.",

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AB - The regulation of glucose metabolism is complex and involves control through hormonal, neuroendocrine, and nutritional factors. Besides the well-known glucoregulatory effects of hormones such as insulin, glucagon, and cortisol, modulation of plasma glucose and insulin also occurs through central and peripheral serotonin signaling. The effects are serotonin receptor-specific, differ between species, and are dependent on the metabolic condition.

KW - Brain

KW - Diabetes

KW - Glucose

KW - Insulin

KW - Insulin resistance

KW - Serotonin (5-HT)

KW - β-cells

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DO - https://doi.org/10.1016/B978-0-444-64125-0.00045-1

M3 - Chapter

VL - 31

T3 - Handbook of Behavioral Neuroscience

SP - 893

EP - 900

BT - Handbook of Behavioral Neuroscience

PB - Elsevier B.V

ER -

Peripheral and central serotonin in the regulation of glucose metabolism

Abstract

Publication series

Keywords

Access to Document

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