TY - JOUR
T1 - Posttraumatic stress disorder with secondary psychotic features: neurobiological findings
AU - Braakman, Mario H.
AU - Kortmann, Frank A. M.
AU - van den Brink, Wim
AU - Verkes, Robbert J.
PY - 2008
Y1 - 2008
N2 - The neurobiological knowledge on the potentially new diagnostic entity "posttraumatic stress disorder with secondary psychotic features" (PTSD-SP) is reviewed. Studies published between 1980 and 2006 were traced focussing on adult patients suffering from this "syndrome". Studies on cortisol, corticotrophin releasing hormone, dopamine beta-hydroxylase, smooth pursuit eye movements and psychopharmacology are described and potential pathophysiological mechanisms briefly discussed. More research is needed to validate the nosological status of PTSD-SP in order to promote neurobiological research and adequate therapeutic interventions
AB - The neurobiological knowledge on the potentially new diagnostic entity "posttraumatic stress disorder with secondary psychotic features" (PTSD-SP) is reviewed. Studies published between 1980 and 2006 were traced focussing on adult patients suffering from this "syndrome". Studies on cortisol, corticotrophin releasing hormone, dopamine beta-hydroxylase, smooth pursuit eye movements and psychopharmacology are described and potential pathophysiological mechanisms briefly discussed. More research is needed to validate the nosological status of PTSD-SP in order to promote neurobiological research and adequate therapeutic interventions
U2 - https://doi.org/10.1016/S0079-6123(07)67027-7
DO - https://doi.org/10.1016/S0079-6123(07)67027-7
M3 - Review article
C2 - 18037029
SN - 0079-6123
VL - 167
SP - 299
EP - 302
JO - Progress in brain research
JF - Progress in brain research
ER -