TY - JOUR
T1 - Pregnancy and Thoracic Aortic Disease: Managing the Risks
AU - Wanga, Shaynah
AU - Silversides, Candice
AU - Dore, Annie
AU - de Waard, Vivian
AU - Mulder, Barbara
PY - 2016
Y1 - 2016
N2 - The most common aortopathies in women of childbearing age are bicuspid aortic valve, coarctation of the aorta, Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome, SMAD3 aortopathy, Turner syndrome, and familial thoracic aneurysm and dissection. The hemodynamic and hormonal changes of pregnancy increase the risk of progressive dilatation or dissection of the aorta in these women. The presence of hypertension increases the risk further. Therefore, appropriate preconception counselling is advised. For women who become pregnant, serial follow-up by a specialized multidisciplinary team throughout pregnancy and postpartum period is required. In this review we discuss risk assessment and management strategies for women with aortopathies
AB - The most common aortopathies in women of childbearing age are bicuspid aortic valve, coarctation of the aorta, Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome, SMAD3 aortopathy, Turner syndrome, and familial thoracic aneurysm and dissection. The hemodynamic and hormonal changes of pregnancy increase the risk of progressive dilatation or dissection of the aorta in these women. The presence of hypertension increases the risk further. Therefore, appropriate preconception counselling is advised. For women who become pregnant, serial follow-up by a specialized multidisciplinary team throughout pregnancy and postpartum period is required. In this review we discuss risk assessment and management strategies for women with aortopathies
U2 - https://doi.org/10.1016/j.cjca.2015.09.003
DO - https://doi.org/10.1016/j.cjca.2015.09.003
M3 - Review article
C2 - 26604124
SN - 0828-282X
VL - 32
SP - 78
EP - 85
JO - Canadian Journal of Cardiology
JF - Canadian Journal of Cardiology
IS - 1
ER -