TY - JOUR
T1 - Primary therapy and survival among patients with nodular lymphocyte-predominant Hodgkin lymphoma
T2 - a population-based analysis in the Netherlands, 1993–2016
AU - Posthuma, Hidde L.A.
AU - Zijlstra, Josée M.
AU - Visser, Otto
AU - Lugtenburg, Pieternella J.
AU - Kersten, Marie José
AU - Dinmohamed, Avinash G.
N1 - Funding Information: The authors thank the registration clerks of the Netherlands Cancer Registry (NCR) for their dedicated data collection. Established in 1989, the nationwide population-based NCR is maintained and hosted by the Netherlands Comprehensive Cancer Organisation (IKNL). Publisher Copyright: © 2019 The Authors. British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - In this nationwide, population-based study, we assessed trends in primary treatment and survival among 687 patients with nodular lymphocyte-predominant Hodgkin lymphoma (75% males; median age, 40 years; and 74% stage-I/II disease) diagnosed in the Netherlands between 1993–2016. There were no noteworthy changes in the application of primary therapy over time among adult patients across the different disease stages and age groups. Survival among various subgroups of adult patients was largely comparable to the expected survival of the general population. A particularly encouraging finding was that young adult patients experienced virtually no excess mortality, as compared to the general population.
AB - In this nationwide, population-based study, we assessed trends in primary treatment and survival among 687 patients with nodular lymphocyte-predominant Hodgkin lymphoma (75% males; median age, 40 years; and 74% stage-I/II disease) diagnosed in the Netherlands between 1993–2016. There were no noteworthy changes in the application of primary therapy over time among adult patients across the different disease stages and age groups. Survival among various subgroups of adult patients was largely comparable to the expected survival of the general population. A particularly encouraging finding was that young adult patients experienced virtually no excess mortality, as compared to the general population.
KW - cancer epidemiology
KW - incidence
KW - nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL)
KW - population-based registry
KW - survival
UR - http://www.scopus.com/inward/record.url?scp=85082561725&partnerID=8YFLogxK
U2 - https://doi.org/10.1111/bjh.16290
DO - https://doi.org/10.1111/bjh.16290
M3 - Article
C2 - 31682006
SN - 0007-1048
VL - 189
SP - 117
EP - 121
JO - British journal of haematology
JF - British journal of haematology
IS - 1
ER -