TY - JOUR
T1 - Pyogenic granuloma: an unrecognized cause of gastrointestinal bleeding
AU - van Eeden, Susanne
AU - Offerhaus, G. Johan A.
AU - Morsink, Folkert H.
AU - van Rees, Bastiaan P.
AU - Busch, Olivier R. C.
AU - van Noesel, Carel J. M.
PY - 2004
Y1 - 2004
N2 - Pyogenic granuloma is a lobular capillary hemangioma that mostly occurs on the skin, but it is also encountered on the mucosal surface of the oral cavity. Only a few cases in other parts of the digestive tract have been reported in Japanese patients. In this report, two Caucasian patients are described, who presented with gastrointestinal bleeding due to the presence of a pyogenic granuloma. One was located in the distal esophagus and could be treated with local excision and laser-photocoagulation therapy. The other one was located in the small intestine and was removed by surgical resection. Although extremely rare, pyogenic granuloma as a cause of gastrointestinal bleeding needs consideration. The lesion is benign, presumably reactive and can be adequately treated by excision or laser photocoagulation. Immunohistochemistry and/or polymerase chain reaction for herpesvirus 8 can reliably distinguish pyogenic granuloma from Kaposi's sarcoma, an important differential diagnosis
AB - Pyogenic granuloma is a lobular capillary hemangioma that mostly occurs on the skin, but it is also encountered on the mucosal surface of the oral cavity. Only a few cases in other parts of the digestive tract have been reported in Japanese patients. In this report, two Caucasian patients are described, who presented with gastrointestinal bleeding due to the presence of a pyogenic granuloma. One was located in the distal esophagus and could be treated with local excision and laser-photocoagulation therapy. The other one was located in the small intestine and was removed by surgical resection. Although extremely rare, pyogenic granuloma as a cause of gastrointestinal bleeding needs consideration. The lesion is benign, presumably reactive and can be adequately treated by excision or laser photocoagulation. Immunohistochemistry and/or polymerase chain reaction for herpesvirus 8 can reliably distinguish pyogenic granuloma from Kaposi's sarcoma, an important differential diagnosis
U2 - https://doi.org/10.1007/s00428-004-1013-5
DO - https://doi.org/10.1007/s00428-004-1013-5
M3 - Article
C2 - 15221476
SN - 0945-6317
VL - 444
SP - 590
EP - 593
JO - Virchows Archiv
JF - Virchows Archiv
IS - 6
ER -