Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

T. J. Postma; M. Klein; C. C.P. Verstappen; J. E.C. Bromberg; M. Swennen; J. A. Langendijk; M. J.B. Taphoorn; P. Scheltens; B. J. Slotman; H. M. Van der Ploeg; N. K. Aaronson; J. J. Heimans

doi:https://doi.org/10.1212/WNL.59.1.121

Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

T. J. Postma, M. Klein, C. C.P. Verstappen, J. E.C. Bromberg, M. Swennen, J. A. Langendijk, M. J.B. Taphoorn, P. Scheltens, B. J. Slotman, H. M. Van der Ploeg, N. K. Aaronson, J. J. Heimans

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Abstract

Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

Original language	English
Pages (from-to)	121-123
Number of pages	3
Journal	Neurology
Volume	59
Issue number	1
DOIs	https://doi.org/10.1212/WNL.59.1.121
Publication status	Published - 9 Jul 2002

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title = "Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma",

abstract = "Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.",

author = "Postma, {T. J.} and M. Klein and Verstappen, {C. C.P.} and Bromberg, {J. E.C.} and M. Swennen and Langendijk, {J. A.} and Taphoorn, {M. J.B.} and P. Scheltens and Slotman, {B. J.} and {Van der Ploeg}, {H. M.} and Aaronson, {N. K.} and Heimans, {J. J.}",

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T1 - Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

AU - Postma, T. J.

AU - Klein, M.

AU - Verstappen, C. C.P.

AU - Bromberg, J. E.C.

AU - Swennen, M.

AU - Langendijk, J. A.

AU - Taphoorn, M. J.B.

AU - Scheltens, P.

AU - Slotman, B. J.

AU - Van der Ploeg, H. M.

AU - Aaronson, N. K.

AU - Heimans, J. J.

PY - 2002/7/9

Y1 - 2002/7/9

N2 - Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

AB - Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

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SN - 0028-3878

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SP - 121

EP - 123

JO - Neurology

JF - Neurology

IS - 1

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Radiotherapy-induced cerebral abnormalities in patients with low-grade glioma

Abstract

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