Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging

Rick Bezemer; Matthieu Legrand; Eva Klijn; Michal Heger; Ivo C. J. H. Post; Thomas M. van Gulik; Didier Payen; Can Ince

doi:https://doi.org/10.1364/OE.18.015054

Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging

Rick Bezemer, Matthieu Legrand, Eva Klijn, Michal Heger, Ivo C. J. H. Post, Thomas M. van Gulik, Didier Payen, Can Ince

Research output: Contribution to journal › Article › Academic › peer-review

49 Citations (Scopus)

Abstract

Laser speckle imaging (LSI) is able to provide full-field perfusion maps of the renal cortex and allows quantification of the average LSI perfusion within an arbitrarily set region of interest and the recovery of LSI perfusion histograms within this region. The aim of the present study was to evaluate the use of LSI for mapping renal cortical microvascular perfusion and to demonstrate the capability of LSI to assess renal perfusion heterogeneities. The main findings were that: 1) full-field LSI measurements of renal microvascular perfusion were highly correlated to single-point LDV measurements; 2) LSI is able to detect differences in reperfusion dynamics following different durations of ischemia; and 3) renal microvascular perfusion heterogeneities can be quantitatively assessed by recovering LSI perfusion histograms

Original language	English
Pages (from-to)	15054-15061
Journal	Optics express
Volume	18
Issue number	14
DOIs	https://doi.org/10.1364/OE.18.015054
Publication status	Published - 2010

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https://doi.org/10.1364/OE.18.015054

Cite this

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title = "Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging",

abstract = "Laser speckle imaging (LSI) is able to provide full-field perfusion maps of the renal cortex and allows quantification of the average LSI perfusion within an arbitrarily set region of interest and the recovery of LSI perfusion histograms within this region. The aim of the present study was to evaluate the use of LSI for mapping renal cortical microvascular perfusion and to demonstrate the capability of LSI to assess renal perfusion heterogeneities. The main findings were that: 1) full-field LSI measurements of renal microvascular perfusion were highly correlated to single-point LDV measurements; 2) LSI is able to detect differences in reperfusion dynamics following different durations of ischemia; and 3) renal microvascular perfusion heterogeneities can be quantitatively assessed by recovering LSI perfusion histograms",

author = "Rick Bezemer and Matthieu Legrand and Eva Klijn and Michal Heger and Post, {Ivo C. J. H.} and {van Gulik}, {Thomas M.} and Didier Payen and Can Ince",

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language = "English",

volume = "18",

pages = "15054--15061",

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T1 - Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging

AU - Bezemer, Rick

AU - Legrand, Matthieu

AU - Klijn, Eva

AU - Heger, Michal

AU - Post, Ivo C. J. H.

AU - van Gulik, Thomas M.

AU - Payen, Didier

AU - Ince, Can

PY - 2010

Y1 - 2010

N2 - Laser speckle imaging (LSI) is able to provide full-field perfusion maps of the renal cortex and allows quantification of the average LSI perfusion within an arbitrarily set region of interest and the recovery of LSI perfusion histograms within this region. The aim of the present study was to evaluate the use of LSI for mapping renal cortical microvascular perfusion and to demonstrate the capability of LSI to assess renal perfusion heterogeneities. The main findings were that: 1) full-field LSI measurements of renal microvascular perfusion were highly correlated to single-point LDV measurements; 2) LSI is able to detect differences in reperfusion dynamics following different durations of ischemia; and 3) renal microvascular perfusion heterogeneities can be quantitatively assessed by recovering LSI perfusion histograms

AB - Laser speckle imaging (LSI) is able to provide full-field perfusion maps of the renal cortex and allows quantification of the average LSI perfusion within an arbitrarily set region of interest and the recovery of LSI perfusion histograms within this region. The aim of the present study was to evaluate the use of LSI for mapping renal cortical microvascular perfusion and to demonstrate the capability of LSI to assess renal perfusion heterogeneities. The main findings were that: 1) full-field LSI measurements of renal microvascular perfusion were highly correlated to single-point LDV measurements; 2) LSI is able to detect differences in reperfusion dynamics following different durations of ischemia; and 3) renal microvascular perfusion heterogeneities can be quantitatively assessed by recovering LSI perfusion histograms

U2 - https://doi.org/10.1364/OE.18.015054

DO - https://doi.org/10.1364/OE.18.015054

M3 - Article

C2 - 20639991

SN - 1094-4087

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SP - 15054

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JO - Optics express

JF - Optics express

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