TY - JOUR
T1 - Recent Advances in Pancreatic Cancer Surgery of Relevance to the Practicing Pathologist
AU - van Rijssen, Lennart B.
AU - Rombouts, Steffi J. E.
AU - Walma, Marieke S.
AU - Vogel, Jantien A.
AU - Tol, Johanna A.
AU - Molenaar, Isaac Q.
AU - van Eijck, Casper H. J.
AU - Verheij, Joanne
AU - van de Vijver, Marc J.
AU - Busch, Olivier R. C.
AU - Besselink, Marc G. H.
PY - 2016
Y1 - 2016
N2 - Recent advances in pancreatic surgery have the potential to improve outcomes for patients with pancreatic cancer. We address 3 new, trending topics in pancreatic surgery that are of relevance to the pathologist. First, increasing awareness of the prognostic impact of intraoperatively detected extraregional and regional lymph node metastases and the international consensus definition on lymph node sampling and reporting. Second, neoadjuvant chemotherapy, which is capable of changing 10% to 20% of initially unresectable, to resectable disease. Third, in patients who remain unresectable following neoadjuvant chemotherapy, local ablative therapies may change indications for treatment and improve outcomes
AB - Recent advances in pancreatic surgery have the potential to improve outcomes for patients with pancreatic cancer. We address 3 new, trending topics in pancreatic surgery that are of relevance to the pathologist. First, increasing awareness of the prognostic impact of intraoperatively detected extraregional and regional lymph node metastases and the international consensus definition on lymph node sampling and reporting. Second, neoadjuvant chemotherapy, which is capable of changing 10% to 20% of initially unresectable, to resectable disease. Third, in patients who remain unresectable following neoadjuvant chemotherapy, local ablative therapies may change indications for treatment and improve outcomes
U2 - https://doi.org/10.1016/j.path.2016.05.002
DO - https://doi.org/10.1016/j.path.2016.05.002
M3 - Article
C2 - 27926358
SN - 1875-9157
VL - 9
SP - 539
EP - 545
JO - Surgical pathology clinics
JF - Surgical pathology clinics
IS - 4
ER -