Recent Developments in Thrombin-Activatable Fibrinolysis Inhibitor Research

Pauline F. Marx, Chantal J. N. Verkleij, Mercedes Valls Seron, Joost C. M. Meijers

Research output: Contribution to journalReview articleAcademicpeer-review

12 Citations (Scopus)

Abstract

Thrombin-activatable fibrinolysis inhibitor (TAFI) provides an important molecular link between the coagulation and fibrinolytic systems. In this review, recent major advances in TAFI research, including the elucidation of crystal structures, the development of small inhibitors and the role of TAFI in systems other than hemostasis, are described and discussed
Original languageEnglish
Pages (from-to)1165-1173
JournalMini reviews in medicinal chemistry
Volume9
Issue number10
DOIs
Publication statusPublished - 2009

Cite this