Rewiring biology: Targeting dendritic cells to reset allergic disease

S. Busold

Rewiring biology: Targeting dendritic cells to reset allergic disease

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

In this thesis we have investigated how to innovate allergen immunotherapy (AIT) strategies centered around dendritic cells (DCs) as orchestrators of adaptive immune responses. To that end, we characterized the immunological effects of allergens on DCs and investigated novel therapy candidates. Our data indicate that neither the major HDM allergens Der p 1 and Der p 2, nor the major

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	van Ree, Ronald, Supervisor Geijtenbeek, Theo, Supervisor de Jong, Esther, Co-supervisor Tas, Sander, Co-supervisor Geijtenbeek, T.B.H., Supervisor, External person
Award date	8 Mar 2024
Print ISBNs	9789464836264
Publication status	Published - 2024

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abstract = "In this thesis we have investigated how to innovate allergen immunotherapy (AIT) strategies centered around dendritic cells (DCs) as orchestrators of adaptive immune responses. To that end, we characterized the immunological effects of allergens on DCs and investigated novel therapy candidates. Our data indicate that neither the major HDM allergens Der p 1 and Der p 2, nor the major",

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AB - In this thesis we have investigated how to innovate allergen immunotherapy (AIT) strategies centered around dendritic cells (DCs) as orchestrators of adaptive immune responses. To that end, we characterized the immunological effects of allergens on DCs and investigated novel therapy candidates. Our data indicate that neither the major HDM allergens Der p 1 and Der p 2, nor the major

UR - https://pure.uva.nl/ws/files/161841068/Licence_Agreement_co-signed_.pdf

M3 - Phd-Thesis - Research and graduation internal

SN - 9789464836264

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Rewiring biology: Targeting dendritic cells to reset allergic disease

Abstract

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