Risicofactoren voor de ziekte van Parkinson

Bram L. van der Gaag; Dagmar H. Hepp; Jorrit I. Hoff; J. J. Bob van Hilten; Sirwan K. L. Darweesh; Bas R. Bloem; Wilma D. J. van de Berg

Risicofactoren voor de ziekte van Parkinson

Translated title of the contribution: Risk factors for Parkinson's disease: possibilities for prevention and intervention

Bram L. van der Gaag, Dagmar H. Hepp, Jorrit I. Hoff, J. J. Bob van Hilten, Sirwan K. L. Darweesh, Bas R. Bloem, Wilma D. J. van de Berg

Research output: Contribution to journal › Article › Professional

Abstract

Considering age to be the primary risk factor for developing Parkinson's disease and the observation that the Dutch population is rapidly aging, the parkinson prevalence is expected to increase over the coming years, as there is still no cure available for the disease. This has been confirmed by epidemiological data, which show a steady increase of the disease prevalence in the Netherlands for the period 2010-2021. Genetic risk factors only partially explain the disease pathogenesis. Environmental factors, such as exposure to pesticides and trichloroethylene are associated with a higher risk for developing Parkinson's disease. Lifestyle factors such as exercise, caffeine intake and the Mediterranean diet are associated with a lower risk for developing the disease and possibly delay the disease progression. Policy makers and healthcare providers should employ stricter regulations for pesticide use and should stimulate a healthy lifestyle to slow down the increasing prevalence.

Translated title of the contribution	Risk factors for Parkinson's disease: possibilities for prevention and intervention
Original language	Dutch
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	167
Publication status	Published - 6 Sept 2023

Cite this

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title = "Risicofactoren voor de ziekte van Parkinson",

abstract = "Considering age to be the primary risk factor for developing Parkinson's disease and the observation that the Dutch population is rapidly aging, the parkinson prevalence is expected to increase over the coming years, as there is still no cure available for the disease. This has been confirmed by epidemiological data, which show a steady increase of the disease prevalence in the Netherlands for the period 2010-2021. Genetic risk factors only partially explain the disease pathogenesis. Environmental factors, such as exposure to pesticides and trichloroethylene are associated with a higher risk for developing Parkinson's disease. Lifestyle factors such as exercise, caffeine intake and the Mediterranean diet are associated with a lower risk for developing the disease and possibly delay the disease progression. Policy makers and healthcare providers should employ stricter regulations for pesticide use and should stimulate a healthy lifestyle to slow down the increasing prevalence.",

author = "{van der Gaag}, {Bram L.} and Hepp, {Dagmar H.} and Hoff, {Jorrit I.} and {van Hilten}, {J. J. Bob} and Darweesh, {Sirwan K. L.} and Bloem, {Bas R.} and {van de Berg}, {Wilma D. J.}",

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month = sep,

day = "6",

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T1 - Risicofactoren voor de ziekte van Parkinson

AU - van der Gaag, Bram L.

AU - Hepp, Dagmar H.

AU - Hoff, Jorrit I.

AU - van Hilten, J. J. Bob

AU - Darweesh, Sirwan K. L.

AU - Bloem, Bas R.

AU - van de Berg, Wilma D. J.

PY - 2023/9/6

Y1 - 2023/9/6

N2 - Considering age to be the primary risk factor for developing Parkinson's disease and the observation that the Dutch population is rapidly aging, the parkinson prevalence is expected to increase over the coming years, as there is still no cure available for the disease. This has been confirmed by epidemiological data, which show a steady increase of the disease prevalence in the Netherlands for the period 2010-2021. Genetic risk factors only partially explain the disease pathogenesis. Environmental factors, such as exposure to pesticides and trichloroethylene are associated with a higher risk for developing Parkinson's disease. Lifestyle factors such as exercise, caffeine intake and the Mediterranean diet are associated with a lower risk for developing the disease and possibly delay the disease progression. Policy makers and healthcare providers should employ stricter regulations for pesticide use and should stimulate a healthy lifestyle to slow down the increasing prevalence.

AB - Considering age to be the primary risk factor for developing Parkinson's disease and the observation that the Dutch population is rapidly aging, the parkinson prevalence is expected to increase over the coming years, as there is still no cure available for the disease. This has been confirmed by epidemiological data, which show a steady increase of the disease prevalence in the Netherlands for the period 2010-2021. Genetic risk factors only partially explain the disease pathogenesis. Environmental factors, such as exposure to pesticides and trichloroethylene are associated with a higher risk for developing Parkinson's disease. Lifestyle factors such as exercise, caffeine intake and the Mediterranean diet are associated with a lower risk for developing the disease and possibly delay the disease progression. Policy makers and healthcare providers should employ stricter regulations for pesticide use and should stimulate a healthy lifestyle to slow down the increasing prevalence.

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M3 - Article

C2 - 37688454

SN - 0028-2162

VL - 167

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

ER -

Risicofactoren voor de ziekte van Parkinson

Abstract

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